Dr.HIROYUKI OHYAMA.Ph.D

'sohhaku OHYAMA' memorial

Institute of Natural Health Science

Oriental Medicine Research Center
Central Research Laboratories

General Manager
Dr. HIROYUKI　OHYAMA (Ph.D)

Dr. HIROYUKI OHYAMA, Ph.D. Selfportrait in 1999 (April ).

E-mail to Dr.Ohyama.

1)

Age-related difference in synaptosomal membrane fluidity

Hiroyuki Ohyama, Midori Hiramatsu, Norio Ogawa, Akitane Mori

Biochemistry and Molecular Biology International 37,133-140,1995　

Department of Neuroscience, Institute of Molecular and Cellular Medicine, Okayama University Medical

School, 2-5-1 Shikatacho, Okayama 700, Japan and *Division of Medical Science, Institute for Life

Support Technology, Yamagata Technopolis Foundation, Yamagata 683 Kurumanomae, Numagi, Yamagata 990, Japan

2)

Effect of Japanese herbal medicine(TJ-960) on neuronal membrane fluidity of mice

Hiroyuki Ohyama, Midori Hiramatsu, Rei Edamatsu, Akitane Mori

Magnetic Resonance in Medicine 6, 279-281, 1995

3)

Effect of Japanese herbal medicine(TJ-960), on aging

Midori Hiramatsu, Rei Edamatsu, Hiroyuki Ohyama, Akitane Mori

Lipid-Soluble Antioxidants:Biochemistry and Clinical Applications.

pp.535-552,Birkhauser Verlag,Basel,1992

4)

Combined treatment of Japanese herbal medicine(TJ-960)with low dose of dipropylacetate increased the latent time for

pentylenetetrazol induced convulsion and decreased brain lipid peroxidation in mice.

Hiramatsu,M., Liu J, Edamatsu,R., Kadowaki,D., Hamada,H., Ohyama,H., Watanabe,S., Mori,A.

Neuroscience 18, 71-76,1992

5)
Estimation of nitric oxide and nitric oxide synthase activity in SAMP8 mouse brain

Habu,H., Yokoi,I., Kabuto,H., Ohyama,H., Mori,A., Teraoka,H., Komaru,N.

in: The SAM Model of Senescence (T.Takeda, ed.) pp.343-346,Elsevier Science B.V., Amsterdam, 1994

6)

Age-related changes in nitric oxide content and nitric oxide synthase activity

in senescence-accelerated mouse (SAM P8) brain

Yokoi,I., Inada,K., Habu,H., Kabuto,H., Mori,A., Ohyama,H., Iwaya,K., Koyama,S., Nishijima,Y., Nishijima,K.

in: Oxidative Stress and Aging (R.G.Cutler, L.Packer, J.Bertram, A.Mori, eds.)

pp387-391, Birkhauser Verlag, Basel, 1995

7)

UNESCO / Costam Workshop on Lipid-soluble Antioxidants in Biochemistry of Nutrition and Environmental Health

1991.9.21 (Malaysia)

Effect of Japanese herbal medicine(TJ-960), on aging

Midori Hiramatsu, Rei Edamatsu, Hiroyuki Ohyama, Akitane Mori

8)

Society for Free Radical Research 1991.9027 (Paris)

Japanese herbal medicine(TJ-960) affected free radicals, SOD activity,

lipid peroxidation and neurotransmitter in aged rat brain

Midori Hiramatsu, Rei Edamatsu, Hiroyuki Ohyama, Akitane Mori

9)

5th International Congress on Oxygen Radicals 1991.11.18 (Kyoto)

Decreased membrane fluidity in rat synaptosomes induced by active oxygen species,

guanidino compounds and convulsants

Midori Hiramatsu, Rei Edamatsu, Hajime Hamada, Hiroyuki Ohyama, Akitane Mori

10)

5th International Congress on Oxygen Radicals 1991.11.20 (Kyoto)

Antioxidant effects of the extracts of gastrodia fleta bl. and uncaria rhynchophylla (MJQ) jacks

Jiankang Liu, Hajime Hamada, Hiroyuki Ohyama, Akitane Mori.

11)

The First International Conference on Senescence: The SAM Model 1994.3.17 (Kyoto)

Estimation of nitric oxide and nitric oxide synthase activity in SAMP8 mouse brain

Habu,H., Yokoi,I., Kabuto,H., Ohyama,H., Mori,A., Teraoka,H., Komaru,N.

12)

The First International Conference on Oxidative Stress and Aging 1994.3.25 (Hawaii)

Age-associated changes in nitric oxide (NO) content and nitric oxide synthase (NOS) activity

in senescence accelerated mouse (SAM P8) brain

Yokoi,I., Inada,K., Habu,H., Kabuto,H., Mori,A., Ohyama,H., Iwaya,K., Koyama,S., Nishijima,Y., Nishijima,K.

13)

International Conference on Bioradicals Detected by ESR Spectroscopy 1994.6.13 (Yamagata)

Effect of Japanese herbal medicine(TJ-960) on neuronal membrane fluidity of mice

Hiroyuki Ohyama, Midori Hiramatsu, Rei Edamatsu, Akitane Mori

14)

International Symposium on Natural Antioxidants: Molecular Mechanisms and Health Effects (ISNA) 1995.6.21 (Beijin)

Antioxidant defenses of Japanese herbal medicine(TJ-960) , against free radical induced neural cell damages

Akitane Mori, Hajime Hamada, Hiroyuki Ohyama, Midori Hiramatsu, Seiichi Shinohara

Reference

1)

Mixed Japanese Herbs and Age-Related Neuronal Functions

Midori Hiramatsu and Makiko Komatsu

Antioxidant Food Supplements in Human Health,edited by Lester Packer,

Midori Hiramatsu,Toshikazu Yoshikawa,pp.412-428,1999

2)

Effects of Japanese herbal medicine(TJ-960), on neuronal membrane fluidity of mice

Hiroyuki Ohyama,Midori Hiramatsu,Rei Edamatsu,Akitane Mori.

Magnetic Resonance in Medicine 6,279-281,1995

Antioxidant effect of TJ-960, a Japanese herbal medicine, against free radical-induced neuronal cell damage

Akitane Mori, Hajime Hamada, Hiroyuki Ohyama, Midori Hiramatsu, Seiichi Shinohara

International Symposium on Natural Antioxidants: Molecular Mechanisms and Health Effects(ISNA),pp.45-53.1996

Effect of TJ-960 on generalized seizure in amygdaloid kindled cats

Susumu Iizuka, Atsushi Ishige, Kyoji Sekiguchi, Akira Sugimoto, Kouichi Itoh, Masaki Aburada, Eikichi Hosoya, Eiichi Sugaya

Recent Advances in the Pharmacology of Kampo Medicines pp.62-68,1988

Normalizing effect of SK commercial formula on cytochalasin-B distorted neurites using primary cultured neurons of rat cerebeal cortex

Aiko Sugaya, Mitsutoshi Yuzurihara, Tadashi Tsuda, Eiichi Sugaya

J. Ethnopharmacol., 21: 193-199,1987.

Effect of Kampo Medicine Preparations Using the Pathological Model of Dementia

Michihiro Fujiwara

Brain Research Conference for Japanese Kampo Medicine pp.67-81,1990

Estimation of nitric oxide and nitric oxide synthase activity in SAMP8 mouse brain

Habu,H.,Yokoi,I.,Kabuto,H.,Ohyama,H.,Mori,A.,Teraoka,H.,Komaru,N.

The SAM Model of Senescence(T.Takeda,ed.) pp.343-346,

Elsevier Science B.V.,Amsterdam,1994

8)

Mixed Natural Antioxidants

Hiramatsu,M.

Food and Free Radicals,edited by Hiramatsu et al.

Plenum Press,New York,pp.113-117,1997

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References Vol.2

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