$B$*Ld$$9g$o$;$O!"(B
$B4AJ}$r8=BeIB$K3h$+$9!*4AJ}@lLg!!Bg;34AJ}F2Lt6I(B
0283-22-1574$B!JBg;34AJ}$G!"%$%4!&IT0B!&%J%7!K(B
$B$^$G!"$*5$7Z$K$*Ld$$9g$o$;$/$@$5$$!#(B
$BBg;34AJ}F2Lt6I(B
$B4AJ}7r9/AjCL%3!<%J!<$X!"%/%j%C%/!*(B
$B:4LnLq=|$1Bg;UDL$j$N4AJ}@lLg!"Bg;34AJ}F2Lt6I!!(BWeb-Page
$B$X!"#G#o!*!*!*(B
$B0eLtIJ$O;HMQ>e$NCm0U$r$*FI$_$$$?$@$-!"@5$7$/$*;H$$$/$@$5$$!#(B
$B$*Gc$$5a$a$N:]$K$O!"4AJ}$r8=BeIB$K3h$+$9(B $B4AJ}@lLg(B $BBg;34AJ}Lt6I$K!"$*5$7Z$K$4AjCL$/$@$5$$!#(B
$B!V%$%s%?!<%M%C%H$G8+$?!*!W(B
$B$H$*OC$/$@$5$$!#(B
$B!JCm0U!K(B
$B4AJ}@lLg!!Bg;34AJ}F2Lt6I$N!!87A*!"4AJ}Lt!"7r9/?)IJ$N$4CmJ8$O!"Bg;34AJ}Lt6I$K!"D>@\!"$*EEOC!"(BFAX$B!"(BE-mail
$B$K$F$4MQL?$/$@$5$$!#(B
$B$*EEOC!'(B0283-22-1574$B!"(BFAX$B!'(B0283-22-1607$B!"(BE-mail:ohyama@poem.ocn.ne.jp
$B$*BT$ACW$7$F$*$j$^$9!#(B
$B!VBg;34AJ}F2(B $B4AJ}0e3X$H4AJ}7r9/AjCL!W(B
$B!!!!!!!!!!(B$B!!Bg;34AJ}F2Lt6I$NF@0U$H$9$kIB5$!"Bg;34AJ}F2Lt6I$K4AJ}AjCL$N$"$k$4IB5$0lMw!"(B
$B!!!!Bg;34AJ}F2Lt6I(B $B4AJ}7r9/AjCLAk8}!"0e3XGn;NBg;3Gn9T@h@8!"0e3XGn;N>.>>Lw90@h@8$N$4>R2p(B
" THE KAMPO " $B4AJ}(B
$B!!4AJ}Lt(B, How the Japanese Updated Traditional
Herbal Medicine
$B!c4AJ}Lt$N$4I~MQ$r$*9M$($N3'MM$X$N$*4j$$!*!d(B
$B!v4AJ}Lt$N$4I~MQ$K4X$7$^$7$F$O!"(B
$B!V;HMQ>e$NCm0U!W$r$h$/FI$_!"!VMQK!!&MQNL!W$r$h$/
$B$^$?!":#2s!";O$a$F!"4AJ}Lt$N$4I~MQ$r4uK>$5$l$k$*5RMM$O!"(B
$B2<5-!"Ld?GI=$KI,MW;v9`$r5-F~$7$FAw?.$9$k$+!"(B
$B4AJ}AjCL$*?=$79~$_%U%)!<%`(B
$B$*EEOC$K$F!"D>@\!"Bg;34AJ}Lt6I$K!"$4AjCL$/$@$5$$!#(B
$B>I>u!&BN\$7$/$*;G$$$7$?>e$G!"E,@Z$J4AJ}Lt$r%"%I%P%$%9$5$;$FD:$-$^$9!#(B
$B!JBg;34AJ}Lt6I(B / $BL5NA4AJ}AjCLEEOC(B $B#0#2#8#3(B-$B#2#2(B-$B#1#5#7#4(B
/ $B#9!'#0#0!A#1#9!'#0#0!K(B
$B!cCm0U!d(B
$BBg;34AJ}Lt6I!"%G%8%?%kE9J^$G!"$*
$B0J>e!"$h$m$7$/$*4j$$CW$7$^$9!#(B
E-mail to Dr. Ohyama Kampo Pharmacy.
$B!!4AJ}$r8=BeIB$K3h$+$9!*!!4AJ}@lLg!!Bg;34AJ}Lt6I%G%8%?%kE9J^$X!*(B
$BBg;34AJ}F2Lt6I(B $B")(B327-0026$B!!FJLZ8):4Ln;T6b20CgD9D.#2#4#3#2(B
TEL$B!u(BFAX : 0283-22-1574$B!!(B E-mail : ohyama@poem.ocn.ne.jp
$B!!(B$B!!(B
$B4AJ}@lLg!!Bg;34AJ}F2Lt6I!!87A*4AJ}Lt!!%D%`%i4AJ}LtA4IJL\$N2r@b(B
$B2,;3Bg3X0e3XGn;N(B $BFAEgBg3XLt3X=$;N(B $BBg;3Gn9T(B
$B%D%`%i$N!V%P%9%O!<%V!W(B
$B@8Lt%(%-%9$N$/$9$jEr(B
$BM-8z@.J,$O#1#0#0!s@8Lt%(%-%9(B
$BLtMQ!!@8LtF~Ma:^(B
$B!J0eLtIJ!K(B
$BF)$-$H$*$C$?(B $B%0%j!<%s$N$*Er(B
$B@8Lt!J%H%&%-!&%;%s%-%e%&!&%O%^%\%&%U%&!&%A%s%T!&%O%C%+!&%+%_%D%l!K$N(B
$BCj=P%(%-%9$rM-8z@.J,$H$7$?1UBN%?%$%W$N$/$9$jEr$G$9!#(B
$B"(@=IJ$r$*;H$$$N:]$O%Q%C%1!<%8$N$4;HMQ$NCm0U$r$h$/$*FI$_$/$@$5$$!#(B
$BMFNL(B $B#6#5#0(BmL $BDL>o2A3J(B $B#3#4#0#01_(B
$BBg;34AJ}Lt6I!!HNGd2A3J!!#3#4#0#01_!J@G9~!'#3#5#7#01_!K(B
$BMFNL(B $B#6#5#0(BmL$B!_#2!!DL>o2A3J(B $B#6#8#0#01_(B
$BFCJL3d0z2A3J!!#6#2#9#01_!J@G9~!'#6#6#0#51_!K(B
$BMFNL(B $B#6#5#0(BmL$B!_#3!!DL>o2A3J(B $B#1#0#2#0#01_(B
$BFCJL3d0z2A3J!!#9#1#8#01_!J@G9~!'#9#6#3#91_!K(B
$BBg;34AJ}Lt6I$O!"(B
$B87A*$5$l$?4AJ}Lt$r$4Ds6!$5$;$F$$$?$@$/$3$H$G!"(B
$B3'MM$N7r9/@83h$r1~1g$7$F$$$^$9!*(B
$B!JIUO?!K(B
$B%D%`%i0eNEMQ4AJ}@=:^A4IJL\$N2r@b(B
$B4AJ}$r8=BeIB$K3h$+$9!*Bg;34AJ}F2Lt6I(B
$B0e3XGn;N>.>>Lw90@h@8(BDr. YASUHIRO KOMATSU$B!J(BPh.D$B!K(B
$B0e3XGn;NBg;3Gn9T@h@8(BDr. HIROYUKI OHYAMA$B!J(BPh.D$B!K(B
No | $B=hJ}L>(B | $B-!8zG=!&8z2L!!-";HMQL\I8!a>Z!!-#Lt8z!&LtM}(B | $B9=@.@8Lt!&G[9gHf(B |
001 | $B%D%`%i3k:,Er(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$+$C$3$s$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B<+A3H/4@$,$J$/F,DK!"H/G.!"0-4(!"8*$3$jEy$rH<$&Hf3SE*BNNO$N$"$k$b$N$NI!'46KA!"I!$+$I@-<@45(B($B7kKl1j!"3QKl1j!"Cf<*1j!"Y(EmA#1j!"F}A#1j!"%j%s%QA#1j(B)$B!"8*$3$j!">eH>?H$N?@7PDK!"$8$s$^$7$s(B $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$N$"$k?M$G!"1j>I@-$"$k$$$OaVDK@-<@45$N=i4|!"$"$k$$$OK}@-<@45!J8zG=!&8z2L;2>H!K$N5^@-A}0-4|$KMQ$$$k!#(B $B#1!K46KA$J$I$NG.@-<@45$G$O!"=i4|$G0-4(!"H/G.!"F,DK!"9`GXIt$N$3$o$P$j$J$I$,$"$C$F!"<+A3H/4@$rH<$o$J$$>l9g!#(B $B#2!KaVDK@-<@45$G$O6I=j$NaVDK!" $B#3!K45It$,H/@V!" $B-#!VLt8z!&LtM}!W(B $B#1!%93%"%l%k%.!<:nMQ!J%^%&%9!K(B $B#2!%%$%s%U%k%(%s%6%&%#%k%946@w>I$KBP$9$k:nMQ!J%^%&%9!K(B $B#3!%%5%$%H%+%$%s$KBP$9$k:nMQ!J%^%&%9!K(B $B#4!%:nMQ5!=x!!%W%m%9%?%0%i%s%8%s#E(B2$B!J#P#G#E(B2$B!K$KBP$9$k:nMQ!J(Bin vitro$B!K(B |
$BF|6I%+%C%3%s!D(B4.0g,$BF|6I%?%$%=%&!D(B3.0g,$BF|6I%^%*%&!D(B3.0g,$BF|6I%+%s%>%&!D(B2.0g,$BF|6I%1%$%R!D(B2.0g,$BF|6I%7%c%/%d%/!D(B2.0g,$BF|6I%7%g%&%-%g%&!D(B2.0g |
002 | $B%D%`%i3k:,Er2C@n5]?I0P(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$+$C$3$s$H$&$+$;$s$-$e$&$7$s$$(B |
$B-!!V8zG=!&8z2L!W(B $BI!$E$^$j!"C_G?>I!"K}@-I!1j(B $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$N$"$k?M$G!"I!JD!"I!O3!"8eI!O3$J$I$NI!>I>u$rAJ$(!"$3$l$i$N>I>u$,$H$/$KK}@-2=$7$?>l9g$KMQ$$$k!#(B $B#1!KF,DK!"F,=E!"9`GXIt$N$3$o$P$j$J$I$rH<$&>l9g!#(B |
$BF|6I%+%C%3%s!D(B4.0g,$BF|6I%?%$%=%&!D(B3.0g,$BF|6I%^%*%&!D(B3.0g,$BF|6I%+%s%>%&!D(B2.0g,$BF|6I%1%$%R!D(B2.0g,$BF|6I%7%c%/%d%/!D(B2.0g,$BF|6I%;%s%-%e%&!D(B2.0g,$BF|6I%7%g%&%-%g%&!D(B1.0g,$B%7%s%$!D(B2.0g |
003 | $B%D%`%i25;zEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$*$D$8$H$&(B |
$B-!!V8zG=!&8z2L!W(B $BIB>u$,$=$l$[$I7c$7$/$J$/!"BNNO$,Cf0L$G?j $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEY$N?M$N<&<@45$G!">I>u$N$"$^$j7c$7$/$J$$$b$N$KMQ$$$k!#(B $B#1!KJXHk$N798~$N$"$k>l9g!#(B $B#2!KfjLg$^$?$O1"It$NaVDK$dGBaZ$rH<$&>l9g!#(B $B#3!K7ZEY$N=P7l$rH<$&>l9g!#(B |
$BF|6I%H%&%-!D(B6.0g,$BF|6I%5%$%3!D(B5.0g,$BF|6I%*%&%4%s!D(B3.0g,$BF|6I%+%s%>%&!D(B2.0g,$BF|6I%7%g%&%^!D(B1.0g,$BF|6I%@%$%*%&!D(B0.5g |
005 | $B%D%`%i0BCf;6(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$"$s$A$e$&$5$s(B |
$B-!!V8zG=!&8z2L!W(B $B$d$;7?$GJ"It6ZFy$,CP4K$9$k798~$K$"$j!"0_DK$^$?$OJ"DK$,$"$C$F!"$H$-$K6;$d$1!"$2$C$W!"?)M_IT?6!"$O$-$1$J$I$rH<$&I(B:$B?@7P@-0_1j!"K}@-0_1j!"0_%"%H%K!<(B $B-"!V;HMQL\I8!a>Z!W(B $BAi$;7?$GHf3SE*BNNO$NDc2<$7$??M$NK}@-$K7P2a$9$k0_DK$d6;$d$1$N$"$k>l9g$KMQ$$$k!#(B $B#1!K?)J*$N>C2=$,0-$/!"?4c]ItKDK~46!"0-?4!"SREG$J$I$rAJ$($k>l9g!#(B $B#2!KJ"It$OFp |
$BF|6I%1%$%R!D(B4.0g,$BF|6I%(%s%4%5%/!D(B3.0g,$BF|6I%\%l%$!D(B3.0g,$BF|6I%&%$%-%g%&!D(B1.5g,$BF|6I%+%s%>%&!D(B1.0g,$BF|6I%7%e%/%7%c!D(B1.0g,$B%j%g%&%-%g%&!D(B0.5g |
006 | $B%D%`%i==L#GTFGEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$8$e$&$_$O$$$I$/$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B2=G?@-HiIf<@45!&5^@-HiIf<@45$N=i4|!"$8$s$^$7$s!"5^@-<>?>!"?eCn(B $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEY$N?M$NHiIf<@45$G!"45It$O;6H/@-$"$k$$$O!"$S$^$s@-$NH/?>$GJ$$o$l!"^z=P1U$N>/$J$$>l9g$KMQ$$$k!#(B $B#1!K45It$K2=G?$rH<$&$+$"$k$$$O2=G?$r$/$jJV$9>l9g!#(B $B#2!K5(O>2 $B-#!VLt8z!&LtM}!W(B $B#1!%93%"%l%k%.!<:nMQ!J%^%&%9!K(B $B#2!%:nMQ5!=x(B $B!J#1!K9%Cf5e3h@-2=:nMQ!J(Bin vitro$B!K(B $B!J#2!K3h@-;@AG$KBP$9$k:nMQ!J(Bin vitro$B!K(B $B!J#3!KHiIf3Q2=$KBP$9$k:nMQ!J(Bin vitro$B!K(B |
$BF|6I%-%-%g%&!D(B3.0g,$BF|6I%5%$%3!D(B3.0g,$BF|6I%;%s%-%e%&!D(B3.0g,$BF|6I%V%/%j%g%&!D(B3.0g,$BF|6I%\%&%U%&!D(B1.5g,$BF|6I%+%s%>%&!D(B1.0g,$BF|6I%1%$%,%$!D(B1.0g,$BF|6I%7%g%&%-%g%&!D(B1.0g,$B%\%/%=%/!D(B3.0g,$B%I%C%+%D!D(B1.5g |
007 | $B%D%`%iH,L#CO2+4](B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$O$A$_$8$*$&$,$s(B |
$B-!!V8zG=!&8z2L!W(B $BHhO+!"7qBU46Cx$7$/!"G"Mx8:>/$^$?$OIQ?t!"8}3i$7!" $B-"!V;HMQL\I8!a>Z!W(B $BCfG/0J9_;~$KO7Np $B#1!K>eJ"It$KHf$Y$F2 $B#3!KHhO+7qBU46!"9xDK!"8}3i$J$I$rH<$&>l9g!#(B $B-#!VLt8z!&LtM}!W(B $B#1!%E|G"IBM^@):nMQ!J%i%C%H!K(B $B#2!%=[4D4o7O$KBP$9$k:nMQ!J%&%5%.!"%^%&%9!K(B $B#3!%9|Be $B#4!%B$@:5!G=$KBP$9$k:nMQ!J%i%C%H!"%^%&%9!K(B $B#5!%MxG":nMQ!J%i%C%H!K(B $B#6!%7l059_2<:nMQ!J%i%C%H!K(B $B#7!%?UB!$KBP$9$k:nMQ!J%i%C%H!K(B $B#8!%:nMQ5!=x(B $B!J#1!K%"%k%I!<%9%j%@%/%?!<% $B!J#2!KB$@:5!G=$KBP$9$k:nMQ!J%i%C%H!K(B |
$BF|6I%8%*%&!D(B6.0g,$BF|6I%5%s%7%e%f!D(B3.0g,$BF|6I%5%s%d%/!D(B3.0g,$BF|6I%?%/%7%c!D(B3.0g,$BF|6I%V%/%j%g%&!D(B3.0g,$BF|6I%\%?%s%T!D(B2.5g,$BF|6I%1%$%R!D(B1.0g,$B=$<#%V%7Kv!D(B0.5g |
008 | $B%D%`%iBg $B$@$$$5$$$3$H$&(B |
$B-!!V8zG=!&8z2L!W(B $BHf3SE*BNNO$N$"$k?M$G!"JXHk$,$A$G!">eJ"It$,D%$C$F6l$7$/!"<*LD$j!"8*$3$j$J$IH<$&$b$N$NI(B:$BC@@P>I!"C@$N$&1j!"2+aU!"4N5!G=>c32!"9b7l05>I!"G>0n7l!"$8$s$^$7$s!"0_;@2aB?>I!"5^@-0_D2%+%?%k!"0-?4!"SREG!"?)M_IT?6!"<&<@!"E|G"IB!"%N%$%m!<%I(B $B-"!V;HMQL\I8!a>Z!W(B $BBN3J!&BNNO$H$b$K=<l9g$KMQ$$$k!#(B $B#1!K0-?4!"SREG!"5(O>It$N6lK~46$J$I$rH<$&>l9g!#(B $B#2!K8*$3$j!"F,DK!"F,=E!"$a$^$$!"<*LD$j$J$I$rH<$&>l9g!#(B $B-#!VLt8z!&LtM}!W(B $B#1!%4N>c32M^@):nMQ!J%i%C%H!"(Bin vitro$B!K(B $B#2!%4N$N;i $B#5!%=[4D7O$KBP$9$k:nMQ!J%&%5%.!"%i%C%H!"%^%&%9!K(B $B#6!%:nMQ5!=x(B $B!J#1!K4N$N;i |
$BF|6I%5%$%3!D(B6.0g,$BF|6I%O%s%2!D(B4.0g,$BF|6I%*%&%4%s!D(B3.0g,$BF|6I%7%c%/%d%/!D(B3.0g,$BF|6I%?%$%=%&!D(B3.0g,$BF|6I%-%8%D!D(B2.0g,$BF|6I%7%g%&%-%g%&!D(B1.0g,$BF|6I%@%$%*%&!D(B1.0g |
009 | $B%D%`%i>. $B$7$g$&$5$$$3$H$&(B |
$B-!!V8zG=!&8z2L!W(B I.$BBNNOCfEyEY$G>eJ"It$,$O$C$F6l$7$/!"@eB]$r@8$8!"8}CfIT2w!"?)M_IT?6!";~$K$h$jHyG.!"0-?4$J$I$N$"$k$b$N$NI(B:$B=t II.$BK}@-4N1j$K$*$1$k4N5!G=>c32$N2~A1(B $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEY$N?M$G6;OF6lK~$N$"$k>l9g$KMQ$$$k!#(B $B#1!KG.@-<@45$G$O?)M_IT?6!"8}CfIT2w46$J$I$rH<$&>l9g!#(B $B#2!K6;OF6lK~$NG'$a$i$l$k=t $B#3!K?)M_IT?6!"A4?H7qBU46$J$I$rH<$&=t $B#4!K5u $B-#!VLt8z!&LtM}!W(B $B#1!%4N>c32M^@):nMQ!J%i%C%H!K(B $B#2!%4N7lN.NLDc2 $B#4!%4N@~0]2=M^@):nMQ!J%i%C%H!K(B $B#5!%LH1VD4@0:nMQ!J%^%&%9!K(B $B#6!%LH1VJ#9gBN=|5n:nMQ!J%^%&%9!K(B $B#7!%93%"%l%k%.!<:nMQ!J%b%k%b%C%H!K(B $B#8!%931j>I:nMQ!J%i%C%H!K(B $B#9!%:nMQ5!=x(B $B!J#1!K4N>c32M^@):nMQ!J(Bin vitro$B!K(B $B!J#2!K4N@~0]2=M^@):nMQ!J(Bin vitro$B!K(B $B!J#3!KLH1VD4@0:nMQ!J%i%C%H!"%^%&%9!"(Bin vitro$B!K(B $B!J#4!K93%"%l%k%.!<:nMQ!J(Bin vitro$B!K(B $B!J#5!K931j>I:nMQ!J(Bin vitro$B!K(B $B!J#6!K3h@-;@AGM^@):nMQ!J(Bin vitro$B!K(B |
$BF|6I%5%$%3!D(B7.0g,$BF|6I%O%s%2!D(B5.0g,$BF|6I%*%&%4%s!D(B3.0g,$BF|6I%?%$%=%&!D(B3.0g,$BF|6I%K%s%8%s!D(B3.0g,$BF|6I%+%s%>%&!D(B2.0g,$BF|6I%7%g%&%-%g%&!D(B1.0g, |
010 | $B%D%`%i $B$5$$$3$1$1$$$7$H$&(B |
$B-!!V8zG=!&8z2L!W(B $BH/G.4@=P$F!"0-4($7!"?HBNDK$_!"F,DK!"$O$-$1$N$"$k$b$N$NI(B:$B46KA!&N.46!&GY1j!&GY7k3K$J$I$NG.@-<@45!"0_DYag!&==Fs;XD2DYag!&C@$N$&1j!&C@@P!&4N5!G=>c32!&g9B!1j$J$I$N?42 $B-"!V;HMQL\I8!a>Z!W(B $BG.@-<@45$G$O!"5^@-4|$r7P$F$J$*F,DK!"0-46!"4X@aDK!"?)M_IT?6$J$I$N$"$k>l9g$KMQ$$$k!#K}@-<@45$G$O!"?4c]It$h$j5(O>It$K$+$1$F6lK~46$rAJ$(!"Dq93!&05DK$,G'$a$i$l!J6;OF6lK~!K!"J"D>6Z$NZ;5^$rH<$&>l9g$KMQ$$$k!#(B $B#1!K?4c]It$N6lK~46!"?)M_IT?6!"J"DK$J$I$rH<$&>l9g!#(B $B#2!K@:?@IT0B!"ITL2$J$I$N@:?@?@7P>I>u$rH<$&>l9g!#(B $B-#!VLt8z!&LtM}!W(B $B#1!%93DYag:nMQ!J%i%C%H!K(B $B#2!%4N>c32M^@):nMQ!J%i%C%H!"%^%&%9!K(B $B#3!%g91jM^@):nMQ!J%i%C%H!K(B $B#4!%:nMQ5!=x(B $B!J#1!K93DYag:nMQ!J(Bin vitro$B!K(B $B!J#2!Kg91jM^@):nMQ!J(Bin vitro$B!K(B $B!J#3!KLH1VD4@0:nMQ!J(Bin vitro$B!K(B $B!J#4!K>C2=4I%[%k%b%s$KBP$9$k:nMQ!J%i%C%H!K(B $B!J#5!K3h@-;@AG>C5n:nMQ!J(Bin vitro$B!K(B |
$BF|6I%5%$%3!D(B5.0g,$BF|6I%O%s%2!D(B4.0g,$BF|6I%*%&%4%s!D(B2.0g,$BF|6I%+%s%>%&!D(B2.0g,$BF|6I%1%$%R!D(B2.0g,$BF|6I%7%c%/%d%/!D(B2.0g,$BF|6I%?%$%=%&!D(B2.0g,$BF|6I%K%s%8%s!D(B2.0g,$BF|6I%7%g%&%-%g%&!D(B1.0g |
011 | $B%D%`%i $B$5$$$3$1$$$7$+$s$-$g$&$H$&(B |
$B-!!V8zG=!&8z2L!W(B $BBNNO$, $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$NDc2<$7$??M$G!"4i?'$,$9$0$l$:!"HhO+7qBU46$,$"$j!"F0X)!"B)@Z$l!"ITL2$J$I$N@:?@?@7P>I>u$rH<$&>l9g$KMQ$$$k!#(B $B#1!K?4c]It$h$j5(O>2 $B#2!K0-4(!"HyG.!"Ep4@!"8}3i$J$I$rH<$&>l9g!#(B |
$BF|6I%5%$%3!D(B6.0g,$BF|6I%*%&%4%s!D(B3.0g,$BF|6I%+%m%3%s!D(B3.0g,$BF|6I%1%$%R!D(B3.0g,$BF|6I%\%l%$!D(B3.0g,$BF|6I%+%s%>%&!D(B2.0g,$B%+%s%-%g%&!D(B2.0g |
012 | $B%D%`%i $B$5$$$3$+$j$e$&$3$D$\$l$$$H$&(B |
$B-!!V8zG=!&8z2L!W(B $BHf3SE*BNNO$,$"$j!"?4X)P6?J!"ITL2!"$$$i$@$AEy$N@:?@>I>u$N$"$k$b$N$NI(B:$B9b7l05>I!"F0L.9E2=>I!"K}@-?UB!IB!"?@7P?j $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$N$"$k?M$G!"@:?@IT0B!"ITL2!"$$$i$$$i$J$I$N@:?@?@7P>I>u$,$"$j!"6;OF6lK~$N$"$k>l9g!#(B $B#1!KF,DK!"F,=E!"8*$3$j$J$I$rH<$&>l9g!#(B $B#2!KgAK5$KJ"ItBgF0L.$NGoF0$NP6?J$rG'$a$k>l9g!#(B $B-#!VLt8z!&LtM}!W(B $B#1!%93F0L.9E2=:nMQ!J%&%5%.!"%i%C%H!K(B $B#2!%DC@E:nMQ!J%^%&%9!K(B $B#3!%93a[Z;:nMQ!J%^%&%9!K(B $B#4!%:nMQ5!=x(B $B!!!!!!!!93F0L.9E2=:nMQ!J%^%&%9!"(Bin vitro$B!K(B |
$BF|6I%5%$%3!D(B5.0g,$BF|6I%O%s%2!D(B4.0g,$BF|6I%1%$%R!D(B3.0g,$BF|6I%V%/%j%g%&!D(B3.0g,$BF|6I%*%&%4%s!D(B2.5g,$BF|6I%?%$%=%&!D(B2.5g,$BF|6I%K%s%8%s!D(B2.5g,$BF|6I%\%l%$!D(B2.5g,$BF|6I%j%e%&%3%D!D(B2.5g,$BF|6I%7%g%&%-%g%&!D(B1.0g |
014 | $B%D%`%iH>2F_C?4Er(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$O$s$2$7$c$7$s$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B$_$>$*$A$,$D$+$(!"$H$-$K0-?4!"SREG$,$"$j?)M_IT?6$GJ"$,LD$C$FFpJX$^$?$O2 $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEY$N?M$G!"?4c]It$NKDK~46!"J"CfMkLD$,$"$j!"0-46!"SREG!"2 $B#1!K?)M_IT?6!"7ZEY$N>eJ"ItDK$J$I$rH<$&>l9g!#(B $B#2!KIT0B!&ITL2$J$I$N@:?@?@7P>I>u$rH<$&>l9g!#(B $B-#!VLt8z!&LtM}!W(B $B!L%R%H$G$N:nMQ!M(B $B!!!!0_GS=PB%?J:nMQ(B $B!LF0J*$G$N:nMQ!M(B $B!!!!#1!%0_GS=PB%?J:nMQ!J%i%C%H!K(B $B!!!!#2!%0_G4Kl>c32$KBP$9$k:nMQ!J%i%C%H!K(B $B!!!!#3!%@)EG:nMQ!J%U%'%l%C%H!K(B $B!!!!#4!%;__C:nMQ!J%i%C%H!"%^%&%9!K(B $B!!!!#5!%:nMQ5!=x(B $B!!!!!!!J#1!K0_G4KlKI8f:nMQ!J%i%C%H!K(B $B!!!!!!!J#2!K931j>I:nMQ!J%i%C%H!"(Bin vitro$B!K(B $B!!!!!!!J#3!KBgD2?eJ,5[<}P6?J:nMQ!J%i%C%H!K(B |
$BF|6I%O%s%2!D(B5.0g,$BF|6I%*%&%4%s!D(B2.5g,$BF|6I%+%s%>%&!D(B2.5g,$BF|6I%?%$%=%&!D(B2.5g,$BF|6I%K%s%8%s!D(B2.5g,$BF|6I%*%&%l%s!D(B1.0g,$B%+%s%-%g%&!D(B2.5g |
015 | $B%D%`%i2+O"2rFGEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$*$&$l$s$2$I$/$H$&(B |
$B-!!V8zG=!&8z2L!W(B $BHf3SE*BNNO$,$"$j!"$N$\$;5$L#$G!"$$$i$$$i$9$k798~$N$"$k$b$N$NI(B:$BS=7l!"EG7l!"2<7l!"G>0n7l!"9b7l05!"?4X)P6?J!"%N%$%m!<%I!"0_1j(B $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEY$b$7$/$O$=$l0J>e$N?M$G!"$N$\$;5$L#$G4iLL9HD,$7!"@:?@IT0B!"ITL2!"%$%i%$%i$J$I$N@:?@?@7P>I>u$rAJ$($k>l9g$KMQ$$$k!#(B $B#1!K?4c]It$NKDK~46$rAJ$($k>l9g!#(B $B#2!KS=7l!"EG7l!"2<7l$J$I$N=P7l$rH<$&>l9g!#(B $B-#!VLt8z!&LtM}!W(B $B#1!%=[4D7O$KBP$9$k:nMQ!J%i%C%H!K(B $B#2!%0_G4Kl>c32$KBP$9$k:nMQ!J%i%C%H!K(B $B#3!%931j>I:nMQ!J%i%C%H!"%^%&%9!K(B $B#4!%:nMQ5!=x(B $B!!!J#1!K7l>.HD6E=8M^@):nMQ!J(Bin vitro$B!K(B $B!!!J#2!K931j>I:nMQ!J(Bin vitro$B!K(B |
$BF|6I%*%&%4%s!D(B3.0g,$BF|6I%*%&%l%s!D(B2.0g,$BF|6I%5%s%7%7!D(B2.0g,$BF|6I%*%&%P%/!D(B1.5g |
016 | $B%D%`%iH>2F8|KQEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$O$s$2$3$&$\$/$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B5$J,$,$U$5$$$G!"0v9"!"?)F;It$K0[J*46$,$"$j!"$H$-$KF0X)!"$a$^$$!"SR5$$J$I$rH<$&I!'IT0B?@7P>I!"?@7P@-0_1j!"$D$o$j!"$;$-!"$7$o$,$l@I!"ITL2>I(B $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEY0J2<$N?M$G!"4i?'$,$9$0$l$:!"?@7P>IE*798~$,$"$j!"0v9"$,:I$,$k46$8!J$$$o$f$k%R%9%F%j!<5e!K$rAJ$($k>l9g$KMQ$$$k!#(B $B#1!K5$J,$,$U$5$.!"ITL2!"F0X)!"@:?@IT0B$J$I$rAJ$($k>l9g!#(B $B#2!K8F5[:$Fq!"31SV!"6;DK$J$I$rH<$&>l9g!#(B $B#3!K?4c]It$N?6?e2;$rH<$&>l9g!#(B |
$BF|6I%O%s%2!D(B6.0g,$BF|6I%V%/%j%g%&!D(B5.0g,$BF|6I%3%&%\%/!D(B3.0g,$BF|6I%=%h%&!D(B2.0g,$BF|6I%7%g%&%-%g%&!D(B1.0g |
017 | $B%D%`%i8^Nj;6(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$4$l$$$5$s(B |
$B-!!V8zG=!&8z2L!W(B $B8}3i!"G"NL8:>/$9$k$b$N$NI(B:$BIb I!"=k5$$"$?$j!"E|G"IB(B I>u$rH<$&>l9g!#(B |
$BF|6I%?%/%7%c!D(B4.0g,$BF|6I%=%&%8%e%D!D(B3.0g,$BF|6I%A%g%l%$!D(B3.0g,$BF|6I%V%/%j%g%&!D(B3.0g,$BF|6I%1%$%R!D(B1.5g |
018 | $B%D%`%i7K;^2C[2ImEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$1$$$7$+$8$e$D$V$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B4X@aDK!"?@7PDK(B $B-"!V;HMQL\I8!a>Z!W(B $BNd$(@-$GHf3SE*BNNO$NDc2<$7$??M$,!";M;h4X@a$NaVDK!" $B#1!K4X@aDK$,$"$j!"4(Nd$K$h$jA~0-$9$k>l9g!#(B $B#2!KHyG.!"Ep4@!"D+$N |
$BF|6I%1%$%R!D(B4.0g,$BF|6I%7%c%/%d%/!D(B4.0g,$BF|6I%=%&%8%e%D!D(B4.0g,$BF|6I%?%$%=%&!D(B4.0g,$BF|6I%+%s%>%&!D(B2.0g,$BF|6I%7%g%&%-%g%&!D(B1.0g,$B=$<#%V%7Kv!D(B0.5g |
019 | $B%D%`%i>.@DN5Er(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$7$g$&$;$$$j$e$&$H$&(B |
$B-!!V8zG=!&8z2L!W(B 1 $B2<5-<@45$K$*$1$k?eMM$Nab!"?eMMI!=A!"I!JD!"$/$7$c$_!"SCLD!"31SV!"N.N^!!5$4I;YSCB)!"I!1j!"%"%l%k%.!]@-I!1j!"%"%l%k%.!]@-7kKl1j!"46KA!!(B2 $B5$4I;Y1j(B $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEY$N?M$G!"SCLD!"31SV!"8F5[:$Fq!"I!>I>u$J$I$rAJ$($k>l9g$KMQ$$$k!#(B $B#1!KK"Kw?eMM@-$Nab!"?eMM@-I!=A!"$/$7$c$_$J$I$rH<$&>l9g!#(B $B#2!K?4c]It$K?6?e2;$rG'$a$k>l9g!#(B $B-#!VLt8z!&LtM}!W(B $B#1!%93%"%l%k%.!I:nMQ!J%b%k%b%C%H!"%i%C%H!"(Bin vitro$B!K(B $B#2!%%&%#%k%946@w$KBP$9$k:nMQ!J%^%&%9!K(B $B#3!%:nMQ5!=x(B $B!!!J#1!K%1%_%+%k%a%G%#%(!<%?!<;:@8!&M7N%M^@):nMQ!J(Bin vitro$B!K(B $B!!!J#2!K1j>I:YK&$KBP$9$k:nMQ!J(Bin vitro$B!K(B $B!!!J#3!K%"%;%A%k%3%j%s;I7c$KBP$9$k:nMQ!J(Bin vitro$B!K(B $B!!!J#4!K%&%#%k%946@w$KBP$9$k:nMQ!J%^%&%9!K(B |
$BF|6I%O%s%2!D(B6.0g,$BF|6I%+%s%>%&!D(B3.0g,$BF|6I%1%$%R!D(B3.0g,$BF|6I%4%_%7!D(B3.0g,$BF|6I%5%$%7%s!D(B3.0g,$BF|6I%7%c%/%d%/!D(B3.0g,$BF|6I%^%*%&!D(B3.0g,$B%+%s%-%g%&!D(B3.0g |
020 | $B%D%`%iKI8J2+fMEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$\$&$$$*$&$.$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B?'Gr$G6ZFyFp$i$+$/?e$V$H$j$NBN.JXITMx$G2<;h$KIb I!'?U1j!"%M%U%m!<%I!"4X@a1j!"a~!"$;$D!"6Z1j!"Ib I!"7n7PIT=g(B /!"4X@a!J$H$/$KI(4X@a!K$N |
$BF|6I%*%&%.!D(B5.0g,$BF|6I%\%&%$!D(B5.0g,$BF|6I%=%&%8%e%D!D(B3.0g,$BF|6I%?%$%=%&!D(B3.0g,$BF|6I%+%s%>%&!D(B1.5g,$BF|6I%7%g%&%-%g%&!D(B1.0g |
021 | $B%D%`%i>.H>2F2Ch*NjEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$7$g$&$O$s$2$+$V$/$j$g$&$H$&(B |
$B-!!V8zG=!&8z2L!W(B $BBNNOCfEyEY$NI(B:$BG%?1SREG(B($B$D$o$j(B)$B!"$=$N$[$+$N=tIB$NSREG(B($B5^@-0_D21j!"<>@-6;Kl1j!"?e I(B) |
$BF|6I%O%s%2!D(B6.0g,$BF|6I%V%/%j%g%&!D(B5.0g,$BF|6I%7%g%&%-%g%&!D(B1.5g |
022 | $B%D%`%i>CIw;6(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$7$g$&$U$&$5$s(B |
$B-!!V8zG=!&8z2L!W(B $BJ,HgJ*$,B?$/!"$+$f$_$N6/$$K}@-$NHiIfIB(B($B<>?>!"i!Kc?>!"?eCn!"$"$;$b!"HiIf$=$&aZ>I(B) $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$N$"$k?M$NK}@-$NHiIf<@45$G!"45It$KG.46$,$"$C$F!"B?$/$O<>=a$7!"GBaZ$N$O$J$O$@$7$$>l9g$KMQ$$$k!#(B $B#1!K4h8G$JHi?>$G!"J,HgJ*$,$"$C$FaPHi$r7A@.$7!"$=$N308+$,1xcR$GCOH)$K@VL#$rBS$S!"8}3i$rAJ$($k>l9g!#(B $B#2!KHiIf$NIBJQ$,2F4|$K$`$+$C$F!"A~0-$9$k798~$N$"$k>l9g!#(B $B-#!VLt8z!&LtM}!W(B $B#1!%93%R%9%?%_%s:nMQ!J%$%L!K(B $B#2!%93%"%l%k%.!<:nMQ!J%^%&%9!K(B $B#3!%:nMQ5!=x(B $B!!!J#1!K93%R%9%?%_%s:nMQ!J(Bin vitro$B!K(B $B!!!J#2!K931j>I:nMQ!J(Bin vitro$B!K(B |
$BF|6I%;%C%3%&!D(B3.0g,$BF|6I%8%*%&!D(B3.0g,$BF|6I%H%&%-!D(B3.0g,$BF|6I%=%&%8%e%D!D(B2.0g,$BF|6I%\%&%U%&!D(B2.0g,$BF|6I%b%/%D%&!D(B2.0g,$BF|6I%A%b!D(B1.5g,$BF|6I%+%s%>%&!D(B1.0g,$BF|6I%/%8%s!D(B1.0g,$BF|6I%1%$%,%$!D(B1.0g,$B%4%\%&%7!D(B2.0g,$B%4%^!D(B1.5g,$B%<%s%?%$!D(B1.0g |
023 | $B%D%`%iEv5"giLt;6(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$H$&$-$7$c$/$d$/$5$s(B |
$B-!!V8zG=!&8z2L!W(B $B6ZFy$,0lBN$KFp ?HIT?q!"?4B!J[Kl>I(B l9g$KMQ$$$k!#(B |
$BF|6I%7%c%/%d%/!D(B4.0g,$BF|6I%=%&%8%e%D!D(B4.0g,$BF|6I%?%/%7%c!D(B4.0g,$BF|6I%V%/%j%g%&!D(B4.0g,$BF|6I%;%s%-%e%&!D(B3.0g,$BF|6I%H%&%-!D(B3.0g |
024 | $B%D%`%i2CL#mvMZ;6(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$+$_$7$g$&$h$&$5$s(B |
$B-!!V8zG=!&8z2L!W(B $BBN $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*5u $B#1!K8*$3$j!"F,DK!"$a$^$$!">eH>?H$N<^G.46!"H/:n@-$NH/4@$J$I$rH<$&>l9g!#(B $B#2!K?4c]It!&5(O>It$K7ZEY$NDq93!&05DK$N$"$k>l9g!#!J6;OF6lK~!K(B $B#3!K@-<~4|$K4XO"$7$F>e5-@:?@?@7P>I>u$rAJ$($k>l9g!#(B $B-#!VLt8z!&LtM}!W(B $B#1!%99G/4|>c32$KBP$9$k:nMQ!J%^%&%9!K(B $B#2!%:nMQ5!=x(B $B!!!!!!!!FbJ,Hg7O$X$N:nMQ!J%^%&%9!K(B |
$BF|6I%5%$%3!D(B3.0g,$BF|6I%7%c%/%d%/!D(B3.0g,$BF|6I%=%&%8%e%D!D(B3.0g,$BF|6I%H%&%-!D(B3.0g,$BF|6I%V%/%j%g%&!D(B3.0g,$BF|6I%5%s%7%7!D(B2.0g,$BF|6I%\%?%s%T!D(B2.0g,$BF|6I%+%s%>%&!D(B1.5g,$BF|6I%7%g%&%-%g%&!D(B1.0g,$BF|6I%O%C%+!D(B1.0g |
025 | $B%D%`%i7K;^h*Nj4](B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$1$$$7$V$/$j$g$&$,$s(B |
$B-!!V8zG=!&8z2L!W(B $BBN3J$O$7$C$+$j$7$F$$$F@V$i4i$,B?$/!"J"It$OBgBN=<I(B:$B;R5\JB$S$K$=$NIUB04o$N1j>I!";R5\FbKl1j!"7n7PIT=g!"7n7P:$Fq!"BS2c32(B($BF,DK!"$a$^$$!"$N$\$;!"8*$3$jEy(B)$B!"Nd$(>I!"J"Kl1j!"BGKP>I!"<&<@45!"bP4]1j(B $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEY$b$7$/$O$=$l0J>e$N?M$G!"$N$\$;$F@V$i4i$N$3$H$,B?$/!"2 $B#1!KF,DK!"8*$3$j!"$a$^$$!"$N$\$;!"B-$NNd$($J$I$rH<$&>l9g!#(B $B#2!KL57n7P!"2aB?7n7P!"7n7P:$Fq$J$I7n7P0[>o$N$"$kIX?M!#(B $B-#!VLt8z!&LtM}!W(B $B#1!%%[%k%b%s$KBP$9$kD4@a:nMQ!J%i%C%H!K(B $B#2!%;R5\$KBP$9$k:nMQ!J%^%&%9!K(B $B#3!%99G/4|>c32$KBP$9$k:nMQ!J%i%C%H!K(B |
$BF|6I%1%$%R!D(B3.0g,$BF|6I%7%c%/%d%/!D(B3.0g,$BF|6I%H%&%K%s!D(B3.0g,$BF|6I%V%/%j%g%&!D(B3.0g,$BF|6I%\%?%s%T!D(B3.0g |
026 | $B%D%`%i7K;^2CN59|24iZEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$1$$$7$+$j$e$&$3$D$\$l$$$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B2 $B-"!V;HMQL\I8!a>Z!W(B $BBN $B#1!K1"0`!"0d@:$J$I$rAJ$($k>l9g$KMQ$$$k!#(B $B#2!K0WHhO+46!"Ep4@!" $B#3!KJ"It$,Fp |
$BF|6I%1%$%R!D(B4.0g,$BF|6I%7%c%/%d%/!D(B4.0g,$BF|6I%?%$%=%&!D(B4.0g,$BF|6I%\%l%$!D(B3.0g,$BF|6I%j%e%&%3%D!D(B3.0,$BF|6I%+%s%>%&!D(B2.0g,$BF|6I%7%g%&%-%g%&!D(B1.5g |
027 | $B%D%`%iKc2+Er(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$^$*$&$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B0-4(!"H/G.!"F,DK!"9xDK!"<+A3$K4@$N=P$J$$$b$N$NI(B:$B46KA!"%$%s%U%k%(%s%6(B($B=i4|$N$b$N(B)$B!"4X@a%j%&%^%A!"SCB)!"F};y$NI!JD:I!"S.F}:$Fq(B $B-"!V;HMQL\I8!a>Z!W(B $BJ?AG$+$i>fIW$GBNNO=<l9g$KMQ$$$k!#(B $B#1!KSCLD!"31SV$J$I$rH<$&>l9g!#(B $B#2!KF}MD;y$N46KA$G!"I!JD:I$N$"$k>l9g!#(B $B-#!VLt8z!&LtM}!W(B $B#1!%%&%#%k%9A}?#M^@):nMQ!J(Bin vitro$B!K(B $B#2!%931j>I:nMQ!J%i%C%H!K(B $B#3!%:nMQ5!=x(B $B!!!J#1!K931j>I:nMQ!J(Bin vitro$B!K(B $B!!!J#2!KH/G.$KBP$9$k:nMQ!J(Bin vitro$B!K(B |
$BF|6I%-%g%&%K%s!D(B5.0g,$BF|6I%^%*%&!D(B5.0,$BF|6I%1%$%R!D(B4.0g,$BF|6I%+%s%>%&!D(B1.5g |
028 | $B%D%`%i1[U92C[2Er(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$($C$T$+$8$e$D$H$&(B |
$B-!!V8zG=!&8z2L!W(B $BIb .JXITMx$N$"$k$b$N$NI(B:$B?U1j!"%M%U%m!<%I!"<>?>(B /$9$k>l9g$KMQ$$$k!#(B |
$BF|6I%;%C%3%&!D(B8.0g,$BF|6I%^%*%&!D(B6.0g,$BF|6I%=%&%8%e%D!D(B4.0g,$BF|6I%?%$%=%&!D(B3.0g,$BF|6I%+%s%>%&!D(B2.0g,$BF|6I%7%g%&%-%g%&!D(B1.0g |
029 | $B%D%`%iG~LgE_Er(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$P$/$b$s$I$&$H$&(B |
$B-!!V8zG=!&8z2L!W(B $Bab$N@Z$l$K$/$$31!"5$4I;Y1j!"5$4I;Y$<$s$=$/(B $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEY$b$7$/$O$=$l0J2<$N?M$N7c$7$$31SV$G!"H/:n@-$K31$,IQH/$7$F4iLL9HD,$9$k>l9g$KMQ$$$k!#(B $B#1!KG4cG$G@Z$l$K$/$$ab$rH<$&>l9g!#(B $B#2!K0v9"$N4%Ag46$d0cOB46$N$"$k>l9g!#(B $B#3!K>e5->I>u$rH<$&O7?M$N31SV!#(B $B-#!VLt8z!&LtM}!W(B $B#1!%DC31:nMQ!J%b%k%b%C%H!K(B $B#2!%5nab:nMQ!J%&%:%i!K(B $B#3!%5$4I;Y3HD%:nMQ!J%b%k%b%C%H!K(B $B#4!%:nMQ5!=x(B $B!!!J#1!K5nab:nMQ!J%&%:%i!"(Bin vitro$B!K(B $B!!!J#2!K93%"%l%k%.!<:nMQ!J(Bin vitro$B!K(B |
$BF|6I%P%/%b%s%I%&!D(B10.0g,$BF|6I%O%s%2!D(B5.0g,$BF|6I%?%$%=%&!D(B3.0g,$BF|6I%+%s%>%&!D(B2.0g,$BF|6I%K%s%8%s!D(B2.0g,$B%3%&%Y%$!D(B5.0g |
030 | $B%D%`%i??IpEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$7$s$V$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B?7DDBeI(B:$B0_D2<@45!"0_D25u $B-"!V;HMQL\I8!a>Z!W(B $B?7DDBel9g$KMQ$$$k!#(B $B#1!KK\J}$N2 $B-#!VLt8z!&LtM}!W(B $B7l059_2<:nMQ!J%i%C%H!K(B |
$BF|6I%V%/%j%g%&!D(B4.0g,$BF|6I%7%c%/%d%/!D(B3.0g,$BF|6I%=%&%8%e%D!D(B3.0g,$BF|6I%7%g%&%-%g%&!D(B1.5g,$B=$<#%V%7Kv!D(B0.5g |
031 | $B%D%`%i8bh%hPEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$4$7$e$f$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$NDc2<$7$?Nd$(>I$N?M$G!"H?I|@-$K5/$3$k7c$7$$F,DK$rAJ$($k>l9g$KMQ$$$k!#(B $B#1!K9`$d8*$N$3$j!"SREG$J$I$rH<$&>l9g!#(B $B#2!K?4c]It$KKDK~46!"a]:I46$"$k$$$O?6?e2;$rG'$a$k>l9g!#(B |
$BF|6I%?%$%=%&!D(B4.0g,$BF|6I%4%7%e%f!D(B3.0g,$BF|6I%K%s%8%s!D(B2.0g,$BF|6I%7%g%&%-%g%&!D(B1.5g |
032 | $B%D%`%i?M;2Er(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$K$s$8$s$H$&(B |
$B-!!V8zG=!&8z2L!W(B $BBNNO5u $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$NDc2<$7$?Nd$(>I$N?M$G!"?)M_IT?6!"0_ItDdBZ46!"2 $B#1!K0_D25u $B#2!KJ"It$,Fp |
$BF|6I%+%s%>%&!D(B3.0g,$BF|6I%=%&%8%e%D!D(B3.0g,$BF|6I%K%s%8%s!D(B3.0g,$B%+%s%-%g%&!D(B3.0g |
033 | $B%D%`%iBg2+24C0HiEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$@$$$*$&$\$?$s$T$H$&(B |
$B-!!V8zG=!&8z2L!W(B $BHf3SE*BNNO$,$"$j!"2 $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$N=<l9g!#(B $B#1!K7n7P:$Fq!"2aB?7n7P$J$I$N7n7P0[>o$N$"$k>l9g!#(B |
$BF|6I%H%&%K%s!D(B4.0g,$BF|6I%\%?%s%T!D(B4.0g,$BF|6I%@%$%*%&!D(B2.0g,$B%H%&%,%7!D(B6.0g,$BL5?e%\%&%7%g%&!D(B1.8 |
034 | $B%D%`%iGr8W2C?M;2Er(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$S$c$C$3$+$K$s$8$s$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B$N$I$N3i$-$H$[$F$j$N$"$k$b$N(B $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$N$"$k?M$G!"BN$,$[$F$j!"8}3i$N$"$k>l9g$KMQ$$$k!#(B $B#1!KB?G"!"HiIfGBaZ46$J$I$rH<$&>l9g!#(B $B-#!VLt8z!&LtM}!W(B $B:nMQ5!=x(B $B!!!!8}3i$KBP$9$k:nMQ!J%i%C%H!K(B |
$BF|6I%;%C%3%&!D(B15.0g,$BF|6I%A%b!D(B5.0g,$BF|6I%+%s%>%&!D(B2.0g,$BF|6I%K%s%8%s!D(B1.5g,$B%3%&%Y%$!D(B8.0g |
035 | $B%D%`%i;M5U;6(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$7$.$c$/$5$s(B |
$B-!!V8zG=!&8z2L!W(B $BHf3SE*BNNO$N$"$k$b$N$G!"Bg $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEY$b$7$/$O$=$l0J>e$N?M$G!"6;OF6lK~!"J"D>6Z$NZ;5^$,$"$j!"%$%i%$%i!"ITL2!"M^$&$D46$J$I$N@:?@?@7P>I>u$rAJ$($k>l9g$KMQ$$$k!#(B $B#1!KJ"DK!"J"ItKDK~46!"F0X)$J$I$rH<$&>l9g!#(B $B-#!VLt8z!&LtM}!W(B $B#1!%93DYag:nMQ!J%i%C%H!K(B $B#2!%4N!&C@F;>c32M^@):nMQ!J%i%C%H!K(B $B#3!%:nMQ5!=x(B $B!!!J#1!K93DYag:nMQ!J%i%C%H!K(B $B!!!J#2!K3h@-;@AG>C5n:nMQ!J(Bin vitro$B!K(B $B!!!J#3!K%W%m%H%s%]%s%W3h@-AK32:nMQ!J(Bin vitro$B!K(B |
$BF|6I%5%$%3!D(B5.0g,$BF|6I%7%c%/%d%/!D(B4.0g,$BF|6I%-%8%D!D(B2.0g,$BF|6I%+%s%>%&!D(B1.5g |
036 | $B%D%`%iLZKIVaEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$b$/$\$&$$$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B4i?'$,$5$($:!"31$r$H$b$J$&8F5[:$Fq$,$"$j!"?4B!2 $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$NDc2<$7$??M$,!"?4c]It$,$D$+$($F9E$/!"8F5[:$Fq!"Ib l9g$KMQ$$$k!#(B |
$BF|6I%;%C%3%&!D(B10.0g,$BF|6I%\%&%$!D(B4.0g,$BF|6I%1%$%R!D(B3.0g,$BF|6I%K%s%8%s!D(B3.0g |
037 | $B%D%`%iH>2FGr[2E7KcEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$O$s$2$S$c$/$8$e$D$F$s$^$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B0_D25u $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$NDc2<$7$?0_D25u $B#1!K0-?4!"SREG!"?)M_IT?6!"A4?H7qBU46$J$I$rH<$&>l9g!#(B $B#2!KJ"It$,Fp |
$BF|6I%A%s%T!D(B3.0g,$BF|6I%O%s%2!D(B3.0g,$BF|6I%S%c%/%8%e%D!D(B3.0g,$BF|6I%V%/%j%g%&!D(B3.0g,$BF|6I%*%&%.!D(B1.5g,$BF|6I%?%/%7%c!D(B1.5g,$BF|6I%K%s%8%s!D(B1.5g,$BF|6I%*%&%P%/!D(B1.0g,$BF|6I%7%g%&%-%g%&!D(B0.5g,$B%F%s%^!D(B2.0g,$B%P%/%,!D(B2.0g,$B%+%s%-%g%&!D(B1.0g |
038 | $B%D%`%iEv5";M5U2C8bh%hP@8U*Er(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$H$&$-$7$.$c$/$+$4$7$e$f$7$g$&$-$g$&$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B $B-"!V;HMQL\I8!a>Z!W(B $BJ?AG$h$jNd$(>I$GBN $B#1!KF,DK!"0-?4!"SREG$J$I$rH<$&>l9g!#(B $B#2!K2 |
$BF|6I%?%$%=%&!D(B5.0g,$BF|6I%1%$%R!D(B3.0g,$BF|6I%7%c%/%d%/!D(B3.0g,$BF|6I%H%&%-!D(B3.0g,$BF|6I%b%/%D%&!D(B3.0g,$BF|6I%+%s%>%&!D(B2.0g,$BF|6I%4%7%e%f!D(B2.0g,$BF|6I%5%$%7%s!D(B2.0g,$BF|6I%7%g%&%-%g%&!D(B1.0g |
039 | $B%D%`%iNj7K[24EEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$j$g$&$1$$$8$e$D$+$s$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B$a$^$$!"$U$i$D$-$,$"$j!"$^$?$OF0X)$,$"$jG"NL$,8:>/$9$k$b$N$NI!'?@7P $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$NDc2<$7$??M$G!"$a$^$$!"?HBNF0MI46!"$?$A$/$i$_$J$I$rAJ$($k>l9g$KMQ$$$k!#(B $B#1!KB)@Z$l!"?4X)P6?J!"F,DK!"$N$\$;!"G"NL8:>/$J$I$rH<$&>l9g!#(B $B#2!K?4c]It$K?6?e2;$rG'$a$k>l9g!#(B |
$BF|6I%V%/%j%g%&!D(B6.0g,$BF|6I%1%$%R!D(B4.0g,$BF|6I%=%&%8%e%D!D(B3.0g,$BF|6I%+%s%>%&!D(B2.0g |
040 | $B%D%`%iCvNjEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$A$g$l$$$H$&(B |
$B-!!V8zG=!&8z2L!W(B $BG"NL8:>/!">.JXFq!"8}3i$rAJ$($k$b$N$NI(B:$BG"F;1j!"?UB!1j!"?U@P>I!"NT1j!"GSG"DK!"7lG"!"9x0J2<$NIb
|
$BF|6I%?%/%7%c!D(B3.0g,$BF|6I%A%g%l%$!D(B3.0g,$BF|6I%V%/%j%g%&!D(B3.0g,$B%"%-%g%&!D(B3.0g,$B%+%C%;%-!D(B3.0g |
041 | $B%D%`%iJdCf1W5$Er(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$[$A$e$&$($C$-$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B>C2=5!G=$,?j$(!";M;h7qBU46Cx$7$$5u $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$NDc2<$7$??M$,!"A4?H7qBU46!"?)M_IT?6$J$I$rAJ$($k>l9g$KMQ$$$k!#(B $B#1!K5u $B#2!K=Q8e!"IB8e!";:8e$J$I$G?j $B#3!K31SV!"HyG.!"Ep4@!"F0X)$J$I$rH<$&>l9g!#(B $B-#!VLt8z!&LtM}!W(B $B#1!%IB8e$NBNNODc2<$KBP$9$k:nMQ!J%i%C%H!"%^%&%9!K(B $B#2!%9bNp $B#4!%:nMQ5!=x(B $B!!!J#1!KGr7l5e$KBP$9$k:nMQ!J%^%&%9!K(B $B!!!J#2!KLH1VD4@0:nMQ!J%i%C%H!"%^%&%9!"(Bin vitro$B!K(B $B!!!J#3!K@:Ac$KBP$9$k:nMQ!J(Bin vitro$B!K(B |
$BF|6I%*%&%.!D(B4.0g,$BF|6I%=%&%8%e%D!D(B4.0g,$BF|6I%K%s%8%s!D(B4.0g,$BF|6I%H%&%-!D(B3.0g,$BF|6I%5%$%3!D(B2.0g,$BF|6I%?%$%=%&!D(B2.0g,$BF|6I%A%s%T!D(B2.0g,$BF|6I%+%s%>%&!D(B1.5g,$BF|6I%7%g%&%^!D(B1.0g,$BF|6I%7%g%&%-%g%&!D(B0.5g |
043 | $B%D%`%iO;7/;REr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$j$C$/$s$7$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B0_D2$N $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$NDc2<$7$??M$,0_D25!G=$,Dc2<$7$F!"?)M_IT?6!"?4c]It$NKDK~46$J$I$rAJ$($k>l9g$KMQ$$$k!#(B $B#1!KA4?H7qBU46!" $B#2!KJ"JI$N6[D%$, $B-#!VLt8z!&LtM}!W(B $B!L%R%H$G$N:nMQ!M(B $B!!#1!%0_GS=PB%?J:nMQ(B $B!!#2!%0_G4Kl7lN.NLA}2C:nMQ(B $B!!#3!%0_G4KlEE0L:9!J(Bpotential difference$B!KDc2 $B!!#1!%>C2=4I1?F0P6?J:nMQ!J%$%L!K(B $B!!#2!%0_E,1~@-CP4K$KBP$9$k:nMQ!J(Bin vitro$B!K(B $B!!#3!%0_G4Kl>c32$KBP$9$k:nMQ!J%i%C%H!K(B $B!!#4!%0_G4Kl7lN.Dc2 $B!!#6!%2CNp$KH<$&>.D2G4Kl$NJQ2=$KBP$9$k:nMQ!J%^%&%9!K(B $B!!#7!%:nMQ5!=x(B $B!!!!!J#1!K0_E,1~@-CP4K$KBP$9$k:nMQ!J(Bin vitro$B!K(B $B!!!!!J#2!K0_G4Kl>c32$KBP$9$k:nMQ!J%i%C%H!"(Bin vitro$B!K(B $B!!!!!J#3!K0_;@!&%Z%W%7%s$NJ,HgM^@):nMQ!J(Bin vitro$B!K(B $B!!!!!J#4!K3h@-;@AG>C5n:nMQ!J(Bin vitro$B!K(B |
$BF|6I%=%&%8%e%D!D(B4.0g,$BF|6I%K%s%8%s!D(B4.0g,$BF|6I%O%s%2!D(B4.0g,$BF|6I%V%/%j%g%&!D(B4.0g,$BF|6I%?%$%=%&!D(B2.0g,$BF|6I%A%s%T!D(B2.0g,$BF|6I%+%s%>%&!D(B1.0g,$BF|6I%7%g%&%-%g%&!D(B0.5g |
045 | $B%D%`%i7K;^Er(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$1$$$7$H$&(B |
$B-!!V8zG=!&8z2L!W(B $BBNNO$,?j$($?$H$-$NIw $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$NDc2<$7$??M$GF,DK!"H/G.!"0-46!"?HBNDK$J$I$,$"$j!"<+A3$K4@$N=P$d$9$$>l9g$KMQ$$$k!#(B |
$BF|6I%1%$%R!D(B4.0g,$BF|6I%7%c%/%d%/!D(B4.0g,$BF|6I%?%$%=%&!D(B4.0g,$BF|6I%+%s%>%&!D(B2.0g,$BF|6I%7%g%&%-%g%&!D(B1.5g |
046 | $B%D%`%i<7J*9_2 $B$7$A$b$D$3$&$+$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B?HBN5u $B-"!V;HMQL\I8!a>Z!W(B $BBN $B#1!K0WHhO+46!"2 $B-#!VLt8z!&LtM}!W(B $B7l059_2<:nMQ!J%i%C%H!K(B |
$BF|6I%7%c%/%d%/!D(B4.0g,$BF|6I%H%&%-!D(B4.0g,$BF|6I%*%&%.!D(B3.0g,$BF|6I%8%*%&!D(B3.0g,$BF|6I%;%s%-%e%&!D(B3.0g,$BF|6I%*%&%P%/!D(B2.0g,$B%A%g%&%H%&%3%&!D(B3.0g |
047 | $B%D%`%iD`F#;6(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$A$g$&$H$&$5$s(B |
$B-!!V8zG=!&8z2L!W(B $BK}@-$KB3$/F,DK$GCfG/0J9_!"$^$?$O9b7l05$N798~$N$"$k$b$N(B $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEY$"$k$$$O$d$dDc2<$7$?CfG/0J9_$N?M$G!"K}@-$K7P2a$9$kF,DK!"8*$3$j!"$a$^$$$J$I$rAJ$($k>l9g$KMQ$$$k!#(B $B#1!KD+J}$"$k$$$O$a$6$a;~$KF,DK!"F,=E46$N$"$k$3$H$,B?$$!#(B $B#2!K$N$\$;!"<*LD!"ITL2!"4c5e7kKl$N=<7l$J$I$rH<$&>l9g!#(B |
$BF|6I%;%C%3%&!D(B5.0g,$BF|6I%A%s%T!D(B3.0g,$BF|6I%P%/%b%s%I%&!D(B3.0g,$BF|6I%O%s%2!D(B3.0g,$BF|6I%V%/%j%g%&!D(B3.0g,$BF|6I%K%s%8%s!D(B2.0g,$BF|6I%\%&%U%&!D(B2.0g,$BF|6I%+%s%>%&!D(B1.0g,$BF|6I%7%g%&%-%g%&!D(B1.0g,$B%A%g%&%H%&%3%&!D(B3.0g,$B%-%C%+!D(B2.0g |
048 | $B%D%`%i==A4BgJdEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$8$e$&$<$s$@$$$[$H$&(B |
$B-!!V8zG=!&8z2L!W(B $BIB8e$NBNNODc2 $B-"!V;HMQL\I8!a>Z!W(B $BIB8e!"=Q8e$"$k$$$OK}@-<@45$J$I$G!"HhO+?j $B#1!KA4?H7qBU46!"?)M_IT?6!"4i?'ITNI!"HiIf8OAg!"IO7l$J$I$rH<$&$3$H$,B?$$!#(B $B#2!KEp4@!"8}Fb4%Ag46$J$I$rH<$&>l9g!#(B $B-#!VLt8z!&LtM}!W(B $B#1!%IB8e$NBNNODc2<$KBP$9$k:nMQ!J%i%C%H!"%^%&%9!K(B $B#2!% $B#4!%:nMQ5!=x(B $B!!!!!!LH1VD4@0:nMQ(B $B!!!!!!!J#1!K1U@-LH1V$KBP$9$k:nMQ!J%^%&%9!K(B $B!!!!!!!J#2!K:YK&@-LH1V$KBP$9$k:nMQ!J%^%&%9!K(B $B!!!!!!!J#3!K#N#K3h@-$KBP$9$k:nMQ!J%^%&%9!K(B $B!!!!!!!J#4!K%^%/%m%U%!!<%83h@-$KBP$9$k:nMQ!J%^%&%9!K(B $B!!!!!!!J#5!K%5%$%H%+%$%s;:@8$KBP$9$k:nMQ!J%^%&%9!"(Bin vitro$B!K(B |
$BF|6I%*%&%.!D(B3.0g,$BF|6I%1%$%R!D(B3.0g,$BF|6I%8%*%&!D(B3.0g,$BF|6I%7%c%/%d%/!D(B3.0g,$BF|6I%;%s%-%e%&!D(B3.0g,$BF|6I%=%&%8%e%D!D(B3.0,$BF|6I%H%&%-!D(B3.0g,$BF|6I%K%s%8%s!D(B3.0g,$BF|6I%V%/%j%g%&!D(B3.0g,$BF|6I%+%s%>%&!D(B1.5g |
050 | $B%D%`%i7U3)O"fKEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$1$$$,$$$l$s$.$g$&$H$&(B |
$B-!!V8zG=!&8z2L!W(B $BC_G?>I!"K}@-I!1j!"K}@-Y(Em1j!"$K$-$S(B $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEYA08e$N?M$G!"HiIf$N?'$,@u9u$/!"I{I!9P!"Y(Em$J$I$K1j>I$r5/$3$7$d$9$$>l9g$KMQ$$$k!#(B $B#1!K4iLL!"0v9"!">e5$F;$J$I$KH/$9$kK}@-$N1j>I@-=t<@45!#(B $B-#!VLt8z!&LtM}!W(B $B#1!%936]:nMQ!J(Bin vitro$B!K(B $B#2!%:nMQ5!=x(B $B!!!J#1!K:Bal$KBP$9$k:nMQ!J(Bin vitro$B!K(B $B!!!J#2!K931j>I:nMQ!J(Bin vitro$B!K(B $B!!!J#3!K93%"%l%k%.!<:nMQ!J%^%&%9!K(B |
$BF|6I%*%&%4%s!D(B1.5g,$BF|6I%*%&%P%/!D(B1.5g,$BF|6I%*%&%l%s!D(B1.5g,$BF|6I%-%-%g%&!D(B1.5g,$BF|6I%-%8%D!D(B1.5g,$BF|6I%1%$%,%$!D(B1.5g,$BF|6I%5%$%3!D(B1.5g,$BF|6I%5%s%7%7!D(B1.5g,$BF|6I%8%*%&!D(B1.5g,$BF|6I%7%c%/%d%/!D(B1.5g,$BF|6I%;%s%-%e%&!D(B1.5g,$BF|6I%H%&%-!D(B1.5g,$BF|6I%O%C%+!D(B1.5g,$BF|6I%S%c%/%7!D(B1.5g,$BF|6I%\%&%U%&!D(B1.5g,$BF|6I%l%s%.%g%&!D(B1.5g,$BF|6I%+%s%>%&!D(B1.0g |
051 | $B%D%`%i=aD2Er(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$8$e$s$A$g$&$H$&(B |
$B-!!V8zG=!&8z2L!W(B $BJXHk(B $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEY$"$k$$$O$d$dDc2<$7$??M$NCP4K@-$^$?$Oa[Z;@-JXHk$KMQ$$$k!#(B $B#1!KO7?M$"$k$$$O0_D25!G=$NDc2<$7$??M$NJXHk!#(B $B#2!KHiIf8OAg!"J"JICP4K$7J52t$,?(CN$5$l$k>l9g!#(B |
$BF|6I%8%*%&!D(B6.0g,$BF|6I%H%&%-!D(B3.0g,$BF|6I%*%&%4%s!D(B2.0g,$BF|6I%-%8%D!D(B2.0g,$BF|6I%-%g%&%K%s!D(B2.0g,$BF|6I%3%&%\%/!D(B2.0g,$BF|6I%@%$%*%&!D(B2.0g,$BF|6I%H%&%K%s!D(B2.0g,$BF|6I%+%s%>%&!D(B1.5g,$B%^%7%K%s!D(B2.0g |
052 | $B%D%`%i0Ugo?NEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$h$/$$$K$s$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B4X@aDK!"6ZFyDK(B $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEY$"$k$$$O$=$l0J>e$N?M$G!"Hf3SE*K}@-$K7P2a$9$k;M;h$N4X@a!"6ZFy$NaVDK!" $B-#!VLt8z!&LtM}!W(B $B931j>I:nMQ!J%i%C%H!K(B |
$BF|6I%h%/%$%K%s!D(B8.0g,$BF|6I%=%&%8%e%D!D(B4.0g,$BF|6I%H%&%-!D(B4.0g,$BF|6I%^%*%&!D(B4.0g,$BF|6I%1%$%R!D(B3.0g,$BF|6I%7%c%/%d%/!D(B3.0g,$BF|6I%+%s%>%&!D(B2.0g |
053 | $B%D%`%iAB7P3h7lEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$=$1$$$+$C$1$D$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B4X@aDK!"?@7PDK!"9xDK!"6ZFyDK(B $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEY$N?M$G!"9xIt$h$j2<;h$K$+$1$F$N6ZFy!"4X@a!"?@7P$,DK$`>l9g$KMQ$$$k!#(B $B#1!KNd$($K$h$jA}0-$9$k$3$H$,B?$$!#(B $B#2!K1w7l$rH<$&>l9g!#(B |
$BF|6I%7%c%/%d%/!D(B2.5g,$BF|6I%8%*%&!D(B2.0g,$BF|6I%;%s%-%e%&!D(B2.0g,$BF|6I%=%&%8%e%D!D(B2.0g,$BF|6I%H%&%-!D(B2.0g,$BF|6I%H%&%K%s!D(B2.0g,$BF|6I%V%/%j%g%&!D(B2.0g,$BF|6I%4%7%D!D(B1.5g,$BF|6I%A%s%T!D(B1.5g,$BF|6I%\%&%$!D(B1.5g,$BF|6I%\%&%U%&!D(B1.5g,$BF|6I%j%e%&%?%s!D(B1.5g,$BF|6I%+%s%>%&!D(B1.0g,$BF|6I%S%c%/%7!D(B1.0g,$BF|6I%7%g%&%-%g%&!D(B0.5g,$B%$%l%$%;%s!D(B1.5g,$B%-%g%&%+%D!D(B1.5g |
054 | $B%D%`%iM^4N;6(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$h$/$+$s$5$s(B |
$B-!!V8zG=!&8z2L!W(B $B5u $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEY$N?M$G!"?@7P2aIR$G6=J3$7$d$9$/!"E\$j$d$9$$!"%$%i%$%i$9$k!"L2$l$J$$$J$I$N@:?@?@7P>I>u$rAJ$($k>l9g$KMQ$$$k!#(B $B#1!K$*$A$D$-$,$J$$!"$R$-$D$1!"Lk5c$-$J$I$N$"$k>.;y!#(B $B#2!K4cb[a[Z;$d $B#3!KJ"D>6Z$N6[D%$7$F$$$k>l9g!#(B $B-#!VLt8z!&LtM}!W(B $B93IT0B:nMQ!J%^%&%9!K(B |
$BF|6I%=%&%8%e%D!D(B4.0g,$BF|6I%V%/%j%g%&!D(B4.0g,$BF|6I%;%s%-%e%&!D(B3.0g,$BF|6I%H%&%-!D(B3.0g,$BF|6I%5%$%3!D(B2.0g,$BF|6I%+%s%>%&!D(B1.5g,$B%A%g%&%H%&%3%&!D(B3.0g |
055 | $B%D%`%iKc0I4E@PEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$^$-$g$&$+$s$;$-$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B>.;y$<$s$=$/!"5$4I;Y$<$s$=$/(B $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$N$"$k?M$G!"31SV$,6/$/!"8}3i!"<+A3H/4@!"G.46$J$I$,$"$j!"SCLD!"8F5[:$Fq$J$I$rAJ$($k>l9g$KMQ$$$k!#(B $B#1!KG4cG$G$d$d@Z$l$K$/$$ab$rH<$&>l9g!#(B $B#2!K>.;y$KE,MQ$5$l$k$3$H$,B?$$!#(B $B-#!VLt8z!&LtM}!W(B $B#1!%93%"%l%k%.!<:nMQ!J%i%C%H!K(B $B#2!%:nMQ5!=x(B $B!!!!93%"%l%k%.!<:nMQ!J(Bin vitro$B!K(B |
$BF|6I%;%C%3%&!D(B10.0g,$BF|6I%-%g%&%K%s!D(B4.0g,$BF|6I%^%*%&!D(B4.0g,$BF|6I%+%s%>%&!D(B2.0g |
056 | $B%D%`%i8^NT;6(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$4$j$s$5$s(B |
$B-!!V8zG=!&8z2L!W(B $BIQG"!"GSG"DK!";DG"46(B $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEY$"$k$$$O$d$dDc2<$7$??M$NK}@-$K7P2a$7$?G"O)1j>I$G!"IQG"!"!";DG"46!"GSG"DK$J$I$N$"$k>l9g$KMQ$$$k!#(B |
$BF|6I%V%/%j%g%&!D(B6.0g,$BF|6I%*%&%4%s!D(B3.0g,$BF|6I%+%s%>%&!D(B3.0g,$BF|6I%8%*%&!D(B3.0g,$BF|6I%7%c%<%s%7!D(B3.0g,$BF|6I%?%/%7%c!D(B3.0g,$BF|6I%H%&%-!D(B3.0g,$BF|6I%b%/%D%&!D(B3.0g,$BF|6I%5%s%7%7!D(B2.0g,$BF|6I%7%c%/%d%/!D(B2.0g,$B%+%C%;%-!D(B3.0g |
057 | $B%D%`%i29@60{(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$&$s$;$$$$$s(B |
$B-!!V8zG=!&8z2L!W(B $BHiIf$N?'$D$d$,0-$/!"$N$\$;$k$b$N$KMQ$$$k(B:$B7n7PIT=g!"7n7P:$Fq!"7l$NF;>I!"99G/4|=}32!"?@7P>I(B $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEY$N?M$G!"IT0B!"ITL2!"$N$\$;$J$I$N@:?@?@7P>I>u$,$"$j!"=P7l798~$rH<$&>l9g$KMQ$$$k!#(B $B#1!KHiIf$O2+3l?'$rDh$7!"8OAg$7$F$$$k$3$H$,B?$$!#(B $B#2!K2<7l$N$"$k>l9g$d!"IX?M$G$O;R5\=P7l$d7n7P2aB?$G=P7l$NB?$$>l9g!#(B $B#3!KH/G.!"G.46$,$"$C$FGBaZ46$,6/$/!"J,HgJ*$N>/$J$$HiIf>I>u$rH<$&>l9g!#(B |
$BF|6I%8%*%&!D(B3.0g,$BF|6I%7%c%/%d%/!D(B3.0g,$BF|6I%;%s%-%e%&!D(B3.0g,$BF|6I%H%&%-!D(B3.0g,$BF|6I%*%&%4%s!D(B1.5g,$BF|6I%*%&%P%/!D(B1.5g,$BF|6I%*%&%l%s!D(B1.5g,$BF|6I%5%s%7%7!D(B1.5g |
058 | $B%D%`%i@6>eKIIwEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$;$$$8$g$&$\$&$U$&$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B$K$-$S(B $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$N$"$k?M$N!"4iLL$*$h$SF,It$NH/?>$GH/@V$N6/$$$b$N!"2=G?$7$F$$$k$b$N$J$I$KMQ$$$k!#(B $B#1!K@DG/ $B-#!VLt8z!&LtM}!W(B $B#1!%936]:nMQ!J(Bin vitro$B!K(B $B#2!%:nMQ5!=x(B $B!!!!93%j%Q!<%<:nMQ!J(Bin vitro$B!K(B |
$BF|6I%*%&%4%s!D(B2.5g,$BF|6I%-%-%g%&!D(B2.5g,$BF|6I%5%s%7%7!D(B2.5g,$BF|6I%;%s%-%e%&!D(B2.5g,$BF|6I%O%^%\%&%U%&!D(B2.5g,$BF|6I%S%c%/%7!D(B2.5g,$BF|6I%l%s%.%g%&!D(B2.5g,$BF|6I%*%&%l%s!D(B1.0g,$BF|6I%+%s%>%&!D(B1.0g,$BF|6I%-%8%D!D(B1.0g,$BF|6I%1%$%,%$!D(B1.0g,$BF|6I%O%C%+!D(B1.0g |
059 | $B%D%`%i<#F,al0lJ}(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$B$E$=$&$$$C$]$&(B |
$B-!!V8zG=!&8z2L!W(B $B<>?>!"$/$5!"F}MD;y$N<>?>(B $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$N$"$k?M$N4iLL!"F,It$J$I$N<>?>$G!"J,HgJ*!"$S$i$s!"aPHi$J$IG'$a!"GBaZ46$N$"$k>l9g$KMQ$$$k!#(B $B#1!K>.;y$N<>?>$KMQ$$$i$l$k$3$H$,B?$$!#(B |
$BF|6I%;%s%-%e%&!D(B3.0g,$BF|6I%=%&%8%e%D!D(B3.0g,$BF|6I%l%s%.%g%&!D(B3.0g,$BF|6I%\%&%U%&!D(B2.0g,$BF|6I%+%s%>%&!D(B1.0g,$BF|6I%1%$%,%$!D(B1.0g,$BF|6I%3%&%+!D(B1.0g,$BF|6I%@%$%*%&!D(B0.5g,$B%K%s%I%&!D(B2.0g |
060 | $B%D%`%i7K;^2CgiLtEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$1$$$7$+$7$c$/$d$/$H$&(B |
$B-!!V8zG=!&8z2L!W(B $BJ"ItKDK~46$N$"$kI(B:$B$7$V$jJ"!"J"DK(B $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$NDc2<$7$??M$G!"J"ItKDK~$7!"J"DK$,$"$j!"N"5^8e=E$rH<$&2 $BK\J}$O7K;^2CgiLtBg2+Er$h$j$bN"5^8e=E$"$k$$$OJXHk$,7ZEY$N>l9g$K$h$$!#(B $B#1!KJX0U$r:E$9$,!"2w$/GSJX$7$J$$>l9g!#(B $B#2!K2<:^I~MQ8e$NJ"DK!#(B $B#3!K3+J"=Q8e$KJX$,2wDL$7$J$$>l9g!#(B $B-#!VLt8z!&LtM}!W(B $B#1!%;__C:nMQ!J%^%&%9!K(B $B#2!%D24IM"AwG=$KBP$9$k:nMQ!J%^%&%9!K(B |
$BF|6I%7%c%/%d%/!D(B6.0g,$BF|6I%1%$%R!D(B4.0g,$BF|6I%?%$%=%&!D(B4.0g,$BF|6I%+%s%>%&!D(B2.0g,$BF|6I%7%g%&%-%g%&!D(B1.0g |
061 | $B%D%`%iEm3K>55$Er(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$H$&$+$/$8$g$&$-$H$&(B |
$B-!!V8zG=!&8z2L!W(B $BHf3SE*BNNO$,$"$j!"$N$\$;$FJXHk$7$,$A$J$b$N$NI(B:$B7n7PIT=g!"7n7P:$Fq>I!"7n7P;~$d;:8e$N@:?@IT0B!"9xDK!"JXHk!"9b7l05$N?oH<>I>u(B($BF,DK!"$a$^$$!"8*$3$j(B) $B-"!V;HMQL\I8!a>Z!W(B $BBN3J!"BNNO$N=<.J"5^7k!K!"JXHk$7!"$N$\$;$N$"$k>l9g$KMQ$$$k!#(B $B#1!KF,DK!"$a$^$$!"ITL2!"IT0B!" $B#2!K7n7PIT=g!"7n7P:$Fq$J$I$N$"$kIX?M!#(B |
$BF|6I%H%&%K%s!D(B5.0g,$BF|6I%1%$%R!D(B4.0g,$BF|6I%@%$%*%&!D(B3.0g,$BF|6I%+%s%>%&!D(B1.5g,$BL5?e%\%&%7%g%&!D(B0.9g |
062 | $B%D%`%iKIIwDL@;;6(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$\$&$U$&$D$&$7$g$&$5$s(B |
$B-!!V8zG=!&8z2L!W(B $BJ"It$KHi2<;iKC$,B?$/!"JXHk$,$A$J$b$N$NI(B:$B9b7l05$N?oH<>I>u(B($B$I$&$-!"8*$3$j!"$N$\$;(B)$B!"HnK~>I!"$`$/$_!"JXHk(B $B-"!V;HMQL\I8!a>Z!W(B $BBNNO$N=<l9g$KMQ$$$k!#(B $B-#!VLt8z!&LtM}!W(B $B#1!%HnK~$KBP$9$k:nMQ!J%^%&%9!K(B $B#2!%:nMQ5!=x(B $B!!!!!!3l?';iKCAH?%$N3h@-2=:nMQ!J%^%&%9!K(B |
$BF|6I%*%&%4%s!D(B2.0g,$BF|6I%+%s%>%&!D(B2.0g,$BF|6I%-%-%g%&!D(B2.0g,$BF|6I%;%C%3%&!D(B2.0g,$BF|6I%S%c%/%8%e%D!D(B2.0g,$BF|6I%@%$%*%&!D(B1.5g,$BF|6I%1%$%,%$!D(B1.2g,$BF|6I%5%s%7%7!D(B1.2g,$BF|6I%7%c%/%d%/!D(B1.2g,$BF|6I%;%s%-%e%&!D(B1.2g,$BF|6I%H%&%-!D(B1.2g,$BF|6I%O%C%+!D(B1.2g,$BF|6I%\%&%U%&!D(B1.2g,$BF|6I%^%*%&!D(B1.2g,$BF|6I%l%s%.%g%&!D(B1.2g,$BF|6I%7%g%&%-%g%&!D(B0.3g,$B%+%C%;%-!D(B3.0g,$BL5?e%\%&%7%g%&!D(B0.7g |
063 | $B%D%`%i8^@Q;6(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$4$7$c$/$5$s(B |
$B-!!V8zG=!&8z2L!W(B $BK}@-$K7P2a$7!">I>u$N7c$7$/$J$$I(B:$B0_D21j!"9xDK!"?@7PDK!"4X@aDK!"7n7PDK!"F,DK!"Nd$(>I!"99G/4|=}32!"46KA(B $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEYA08e$N?M$G!"4(Nd$d<>5$$K?/$5$l$F!"9xDK!"2 $B#1!KIO7l5$L#$G!">eH>?H$,G.$72 $B#2!K7n7PIT=g$d7n7P:$Fq$J$I$N$"$kIX?M!#(B |
$BF|6I%=%&%8%e%D!D(B3.0g,$BF|6I%A%s%T!D(B2.0g,$BF|6I%H%&%-!D(B2.0g,$BF|6I%O%s%2!D(B2.0g,$BF|6I%V%/%j%g%&!D(B2.0g,$BF|6I%+%s%>%&!D(B1.0g,$BF|6I%-%-%g%&!D(B1.0g,$BF|6I%-%8%D!D(B1.0g,$BF|6I%1%$%R!D(B1.0g,$BF|6I%3%&%\%/!D(B1.0g,$BF|6I%7%c%/%d%/!D(B1.0g,$BF|6I%7%g%&%-%g%&!D(B1.0g,$BF|6I%;%s%-%e%&!D(B1.0g,$BF|6I%?%$%=%&!D(B1.0g,$BF|6I%S%c%/%7!D(B1.0g,$BF|6I%^%*%&!D(B1.0g |
064 | $B%D%`%i_U4EApEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$7$c$+$s$>$&$H$&(B |
$B-!!V8zG=!&8z2L!W(B $BBNNO$,$*$H$m$($F!"Hh$l$d$9$$$b$N$NF0X)!"B)@Z$l(B $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$NDc2<$7$??M$G!"F0X)!"B)@Z$l$J$I$rAJ$($k>l9g$KMQ$$$k!#(B $B#1!KHiIf$N8OAg!"0WHhO+46!" |
$BF|6I%8%*%&!D(B6.0g,$BF|6I%P%/%b%s%I%&!D(B6.0g,$BF|6I%1%$%R!D(B3.0g,$BF|6I%?%$%=%&!D(B3.0g,$BF|6I%K%s%8%s!D(B3.0g,$BF|6I%7%g%&%-%g%&!D(B1.0g,$B%^%7%K%s!D(B3.0g,$B%7%c%+%s%>%&!D(B3.0g,$B%"%-%g%&!D(B2.0g |
065 | $B%D%`%i5"g#Er(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$-$R$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B5u $B-"!V;HMQL\I8!a>Z!W(B $BBN $B#1!K2<7l!"EG7l$J$I$rH<$&>l9g!#(B $B#2!KEp4@!"A4?H7qBU46!"?)M_IT?6$J$I$rH<$&>l9g!#(B |
$BF|6I%*%&%.!D(B3.0g,$BF|6I%K%s%8%s!D(B3.0g,$BF|6I%S%c%/%8%e%D!D(B3.0g,$BF|6I%V%/%j%g%&!D(B3.0g,$BF|6I%*%s%8!D(B2.0g,$BF|6I%?%$%=%&!D(B2.0g,$BF|6I%H%&%-!D(B2.0g,$BF|6I%+%s%>%&!D(B1.0g,$BF|6I%7%g%&%-%g%&!D(B1.0g,$BF|6I%b%C%3%&!D(B1.0g,$B%5%s%=%&%K%s!D(B3.0g,$B%j%e%&%,%s%K%/!D(B3.0g |
066 | $B%D%`%i;2AI0{(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$8$s$=$$$s(B |
$B-!!V8zG=!&8z2L!W(B $B46KA!"$;$-(B $B-"!V;HMQL\I8!a>Z!W(B $B0_D25u $B#1!KF,DK!"H/G.!"31SV!"S=ab$J$I$rH<$&>l9g!#(B $B#2!K?4c]It$N$D$+$(!"0-?4!"SREG$J$I$N$"$k>l9g!#(B |
$BF|6I%O%s%2!D(B3.0g,$BF|6I%V%/%j%g%&!D(B3.0g,$BF|6I%+%C%3%s!D(B2.0g,$BF|6I%-%-%g%&!D(B2.0g,$BF|6I%A%s%T!D(B2.0g,$BF|6I%?%$%=%&!D(B1.5g,$BF|6I%K%s%8%s!D(B1.5g,$BF|6I%+%s%>%&!D(B1.0g,$BF|6I%-%8%D!D(B1.0g,$BF|6I%=%h%&!D(B1.0g,$BF|6I%7%g%&%-%g%&!D(B0.5g,$B%<%s%3!D(B2.0g |
067 | $B%D%`%i=w?@;6(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$K$g$7$s$5$s(B |
$B-!!V8zG=!&8z2L!W(B $B$N$\$;$H$a$^$$$N$"$k$b$N$NI(B:$B;:A0;:8e$N?@7P>I!"7n7PIT=g!"7l$NF;>I(B $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEY$"$k$$$O$=$l0J>e$N?M$G!"$N$\$;$H$a$^$$$,$"$j!"IT0B!"F0X)!"@:?@IT0B!"ITL2!"F,DK$J$I$N@:?@?@7P>I>u$,$"$k>l9g$KMQ$$$k!#(B $B#1!KK}@-$GB?:L$J>I>u$rAJ$($k>l9g!#(B $B#2!K@-<~4|$KH<$C$F$"$k$$$O;:A0;:8e$K>I>u$rAJ$($k>l9g!#(B |
$BF|6I%3%&%V%7!D(B3.0g,$BF|6I%;%s%-%e%&!D(B3.0g,$BF|6I%=%&%8%e%D!D(B3.0g,$BF|6I%H%&%-!D(B3.0g,$BF|6I%*%&%4%s!D(B2.0g,$BF|6I%1%$%R!D(B2.0g,$BF|6I%K%s%8%s!D(B2.0g,$BF|6I%S%s%m%&%8!D(B2.0g,$BF|6I%*%&%l%s!D(B1.0g,$BF|6I%+%s%>%&!D(B1.0g,$BF|6I%A%g%&%8!D(B1.0g,$BF|6I%b%C%3%&!D(B1.0g |
068 | $B%D%`%igiLt4EApEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$7$c$/$d$/$+$s$>$&$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B5^7c$K$*$3$k6ZFy$N$1$$$l$s$rH<$&aVDK(B $B-"!V;HMQL\I8!a>Z!W(B $B5^7c$K5/$3$k6ZFy!J$*$b$K2<;h!K$Na[Z;@-aVDK$J$i$S$KJ"ItaMDK$rAJ$($k>l9g$KMQ$$$k!#F\I~$"$k$$$OB>$N=hJ}$HJ;MQ$5$l$k$3$H$,B?$$!#(B $B-#!VLt8z!&LtM}!W(B $Ba[=L%b%G%k$K$*$1$k6ZHhO+M^@):nMQ!J%i%C%H!K(B |
$BF|6I%+%s%>%&!D(B6.0g,$BF|6I%7%c%/%d%/!D(B6.0g |
069 | $B%D%`%ih*Nj0{(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$V$/$j$g$&$$$s(B |
$B-!!V8zG=!&8z2L!W(B $BEG$-$1$d6;$d$1$,$"$jG"NL$,8:>/$9$k$b$N$NI(B:$B0_1j!"0_%"%H%K! $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEY$"$k$$$O$d$dDc2<$7$??M$G!"0_Fb$K?eJ,$,DdBZ$7$F$$$k$?$a!"0_ItKDK~46!"?4c]It?6?e2;!"6;$d$1!"0-?4$J$I$N$"$k>l9g$KMQ$$$k!#(B $B#1!K?)M_IT?6!"?4X)P6?J!"G"Mx8:>/$J$I$rH<$&>l9g!#(B |
$BF|6I%V%/%j%g%&!D(B5.0g,$BF|6I%=%&%8%e%D!D(B4.0g,$BF|6I%A%s%T!D(B3.0g,$BF|6I%K%s%8%s!D(B3.0g,$BF|6I%-%8%D!D(B1.5g,$BF|6I%7%g%&%-%g%&!D(B1.0g |
070 | $B%D%`%i9aAI;6(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$3$&$=$5$s(B |
$B-!!V8zG=!&8z2L!W(B $B0_D25u $B-"!V;HMQL\I8!a>Z!W(B $BJ?AG$h$j0_D25u $B#2!K3k:,Er$dKc2+Er$J$I$NKc2+:^$G$O?)M_IT?6$r5/$3$9>l9g!#(B |
$BF|6I%3%&%V%7!D(B4.0g,$BF|6I%=%h%&!D(B2.0g,$BF|6I%A%s%T!D(B2.0g,$BF|6I%+%s%>%&!D(B1.5g,$BF|6I%7%g%&%-%g%&!D(B1.0g |
071 | $B%D%`%i;MJ*Er(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$7$b$D$H$&(B |
$B-!!V8zG=!&8z2L!W(B $BHiIf$,8OAg$7!"?'$D$d$N0-$$BNc32$N$J$$?M$NI(B:$B;:8e$"$k$$$ON.;:8e$NHhO+2sI|!"7n7PIT=g!"Nd$(>I!"$7$b$d$1!"$7$_!"7l$NF;>I(B $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$NDc2<$7$??M$G!" $B#1!K7n7PIT=g!"<+N'?@7P<:D4>I>u$J$I$rH<$&IX?M!#(B $B#2!KJ"ItFp |
$BF|6I%8%*%&!D(B3.0g,$BF|6I%7%c%/%d%/!D(B3.0g,$BF|6I%;%s%-%e%&!D(B3.0g,$BF|6I%H%&%-!D(B3.0g |
072 | $B%D%`%i4EG~Bg\'Er(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$+$s$P$/$?$$$=$&$H$&(B |
$B-!!V8zG=!&8z2L!W(B $BLk5c$-!"$R$-$D$1(B $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$NDc2<$7$??M$G!"@:?@6=J3$,$O$J$O$@$7$/!"IT0B!"ITL2!"$R$-$D$1$J$I$N$"$k>l9g$KMQ$$$k!#(B $B#1!KJ"D>6Z$NZ;5^$7$F$$$k>l9g!#(B |
$BF|6I%?%$%=%&!D(B6.0g,$BF|6I%+%s%>%&!D(B5.0g,$B%7%g%&%P%/!D(B20.0g |
073 | $B%D%`%i $B$5$$$+$s$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B31!"31$K$h$k6;DK(B $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEY$N?M$G!"6/$$31$,=P$F!"ab$,@Z$l$K$/$/!"6;DK$9$k>l9g$KMQ$$$k!#(B $B#1!K?4c]It$h$j5(O>It$K$+$1$F6lK~46$rAJ$(!"Dq93!&05DK$NG'$a$i$l$k>l9g!#!J6;OF6lK~!K(B |
$BF|6I%5%$%3!D(B5.0g,$BF|6I%O%s%2!D(B5.0g,$BF|6I%*%&%4%s!D(B3.0g,$BF|6I%?%$%=%&!D(B3.0g,$BF|6I%K%s%8%s!D(B2.0g,$BF|6I%*%&%l%s!D(B1.5g,$BF|6I%+%s%>%&!D(B1.5g,$BF|6I%7%g%&%-%g%&!D(B1.0g,$B%+%m%K%s!D(B3.0g |
074 | $B%D%`%iD40_>55$Er(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$A$g$&$$$8$g$&$-$H$&(B |
$B-!!V8zG=!&8z2L!W(B $BJXHk(B $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEY$N?M$NJXHk$KMQ$$$k!#(B $B#1!KJ"ItKDK~46$,6/$/!"J"DK$7!"JXHk$9$k>l9g!#(B |
$BF|6I%@%$%*%&!D(B2.0g,$BF|6I%+%s%>%&!D(B1.0g,$BL5?e%\%&%7%g%&!D(B0.5g |
075 | $B%D%`%i;M7/;REr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$7$/$s$7$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B$d$;$F4i?'$,0-$/$F!"?)M_$,$J$/!"$D$+$l$d$9$$$b$N$NI(B:$B0_D25u $B-"!V;HMQL\I8!a>Z!W(B $BBNNO$NDc2<$7$??M$,!"0_D25!G=$,Dc2<$7$F!"?)M_IT?6!"?4c]It$NKDK~46$J$I$rAJ$($k>l9g$KMQ$$$k!#(B $B#1!KA4?H7qBU46!" $B#2!KJ"JI$N6[D%$, $B-#!VLt8z!&LtM}!W(B $B#1!%DYag$KBP$9$k:nMQ!J%i%C%H!K(B $B#2!%@)EG:nMQ!J%$%L!K(B |
$BF|6I%=%&%8%e%D!D(B4.0g,$BF|6I%K%s%8%s!D(B4.0g,$BF|6I%V%/%j%g%&!D(B4.0g,$BF|6I%+%s%>%&!D(B1.0g,$BF|6I%7%g%&%-%g%&!D(B1.0g,$BF|6I%?%$%=%&!D(B1.0g |
076 | $B%D%`%iN5C@_C4NEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$j$e$&$?$s$7$c$+$s$H$&(B |
$B-!!V8zG=!&8z2L!W(B $BHf3SE*BNNO$,$"$j!"2 $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$N$"$k?M$GHgG"4o!"@8?#4oEy$N1j>I$KH<$C$FGSG"DK!"IQG"!"BS2<$J$I$N$"$k>l9g$KMQ$$$k!#(B $B#1!K5^@-$"$k$$$OK}@-$NHgG"4o!&@8?#4o$N1j>I@-<@45!#(B $B#2!K1"ItGBaZ46$rH<$&>l9g!#(B |
$BF|6I%8%*%&!D(B5.0g,$BF|6I%H%&%-!D(B5.0g,$BF|6I%b%/%D%&%&!D(B5.0g,$BF|6I%*%&%4%s!D(B3.0g,$BF|6I%7%c%<%s%7!D(B3.0g,$BF|6I%?%/%7%c!D(B3.0g,$BF|6I%+%s%>%&!D(B1.0g,$BF|6I%5%s%7%7!D(B1.0g,$BF|6I%j%e%&%?%s!D(B1.0g |
077 | $B%D%`%i5]5"g1ghEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$-$e$&$-$-$g$&$,$$$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B<&=P7l(B $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$NDc2<$7$??M$G<&=P7l!"2<7l$J$I$,$"$k>l9g$KMQ$$$k!#(B $B#1!K=P7l$,D9$S$$$F!"IO7l$d$a$^$$!" |
$BF|6I%8%*%&!D(B5.0g,$BF|6I%7%c%/%d%/!D(B4.0g,$BF|6I%H%&%-!D(B4.0g,$BF|6I%+%s%>%&!D(B3.0g,$BF|6I%;%s%-%e%&!D(B3.0g,$B%,%$%h%&!D(B3.0g,$B%"%-%g%&!D(B3.0g |
078 | $B%D%`%iKc0I0U4EEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$^$-$g$&$h$/$+$s$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B4X@aDK!"?@7PDK!"6ZFyDK(B $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$N$"$k?M$,!"=t4X@a$d6ZFy$, l9g$KMQ$$$k!#(B |
$BF|6I%h%/%$%K%s!D(B10.0g,$BF|6I%^%*%&!D(B4.0g,$BF|6I%-%g%&%K%s!D(B3.0g,$BF|6I%+%s%>%&!D(B2.0 |
079 | $B%D%`%iJ?0_;6(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$X$$$$$5$s(B |
$B-!!V8zG=!&8z2L!W(B $B0_$,$b$?$l$F>C2=ITNI$N798~$N$"$kI(B:$B5^!&K}@-0_%+%?%k!"0_%"%H%K!C2=ITNI!"?)M_IT?6(B $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEYA08e$N?M$,!">C2=>c32$r$-$?$7$F?4c]ItIT2w46!"J"ItKDK~46$J$I$rAJ$($k>l9g$KMQ$$$k!#(B $B#1!K?)M_IT?6!"?)8e$NJ"LD!"2 $B#2!K2a?)$J$I$K$h$k5^@-0_D2>c32!#(B |
$BF|6I%=%&%8%e%D!D(B4.0g,$BF|6I%3%&%\%/!D(B3.0g,$BF|6I%A%s%T!D(B3.0g,$BF|6I%?%$%=%&!D(B2.0g,$BF|6I%+%s%>%&!D(B1.0g,$BF|6I%7%g%&%-%g%&!D(B0.5g |
080 | $B%D%`%i $B$5$$$3$;$$$+$s$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B$+$s$N798~$N6/$$798~$N$"$k>.;y$NI(B:$B?@7P>I!"K}@-Y(EmA#1j!"<>?>(B $B-"!V;HMQL\I8!a>Z!W(B $BA#IBI!" $B#1!K>.;y$KMQ$$$i$l$k$3$H$,B?$$!#(B $B#2!KaQ$,6/$/!"ITL2!"Lk5c$-$J$I$N$"$k>l9g!#(B $B#3!KN>J"D>6Z$N6[D%$d!"5(O>2 $B-#!VLt8z!&LtM}!W(B $B93%"%l%k%.!<:nMQ!J%^%&%9!K(B |
$BF|6I%5%$%3!D(B2.0g,$BF|6I%*%&%4%s!D(B1.5g,$BF|6I%*%&%P%/!D(B1.5g,$BF|6I%*%&%l%s!D(B1.5g,$BF|6I%+%m%3%s!D(B1.5g,$BF|6I%+%s%>%&!D(B1.5g,$BF|6I%-%-%g%&!D(B1.5g,$BF|6I%5%s%7%7!D(B1.5g,$BF|6I%8%*%&!D(B1.5g,$BF|6I%7%c%/%d%/!D(B1.5g,$BF|6I%;%s%-%e%&!D(B1.5g,$BF|6I%H%&%-!D(B1.5g,$BF|6I%O%C%+!D(B1.5g,$BF|6I%l%s%.%g%&!D(B1.5g,$B%4%\%&%7!D(B1.5g |
081 | $B%D%`%iFsDDEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$K$A$s$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B0-?4!"SREG(B $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEYA08e$N?M$G0-?4!"SREG!"0_ItIT2w46$J$I$rAJ$($k>l9g$KMQ$$$k!#(B $B#1!K$a$^$$!"F0X)!"F,DK$J$I$rH<$&>l9g!#(B $B#2!K?4c]It$K?6?e2;$rG'$a$k$3$H$,B?$$!#(B |
$BF|6I%O%s%2!D(B5.0g,$BF|6I%V%/%j%g%&!D(B5.0g,$BF|6I%A%s%T!D(B4.0g,$BF|6I%+%s%>%&!D(B1.0g,$BF|6I%7%g%&%-%g%&!D(B1.0g |
082 | $B%D%`%i7K;^?M;2Er(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$1$$$7$K$s$8$s$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B0_D2$N $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$NDc2<$7$??M$G!"?)M_IT?6!"0-?4!"SREG!"0_ItDdBZ46!"2 $B#1!KNd$(>I$G4i?'0-$/Hh$l$d$9$$>l9g!#(B |
$BF|6I%1%$%R!D(B4.0g,$BF|6I%+%s%>%&!D(B3.0g,$BF|6I%=%&%8%e%D!D(B3.0g,$BF|6I%K%s%8%s!D(B3.0g,$B%+%s%-%g%&!D(B2.0g |
083 | $B%D%`%iM^4N;62CDDHiH>2F(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$h$/$+$s$5$s$+$A$s$T$O$s$2(B |
$B-!!V8zG=!&8z2L!W(B $B5u $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$NDc2<$7$??M$G!"?@7P2aIR$G6=J3$7$d$9$/!"E\$j$d$9$$!"%$%i%$%i$9$k!"L2$l$J$$$J$I$N@:?@?@7P>I>u$rAJ$($k>l9g$KMQ$$$k!#(B $B#1!KM^4N;6$KHf$Y!"$h$jBNNO$,Dc2<$7$F>I>u$,$h$jK}@-2=$7$F$$$k$3$H$,B?$$!#(B $B#2!K$*$A$D$-$,$J$/!"$R$-$D$1!"Lk5c$-$J$I$N$"$k>.;y!#(B $B#3!K4cb[a[Z;$d $B#4!KJ"D>6Z$N6[D%$7$F$$$k>l9g!#(B |
$BF|6I%O%s%2!D(B5.0g,$BF|6I%=%&%8%e%D!D(B4.0g,$BF|6I%V%/%j%g%&!D(B4.0g,$BF|6I%;%s%-%e%&!D(B3.0g,$BF|6I%A%s%T!D(B3.0g,$BF|6I%H%&%-!D(B3.0g,$BF|6I%5%$%3!D(B2.0g,$BF|6I%+%s%>%&!D(B1.5g,$B%A%g%&%H%&%3%&!D(B3.0g |
084 | $B%D%`%iBg2+4EApEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$@$$$*$&$+$s$>$&$H$&(B |
$B-!!V8zG=!&8z2L!W(B $BJXHk>I(B $B-"!V;HMQL\I8!a>Z!W(B $B>o=,JXHk$K9-$/MQ$$$k!#(B |
$BF|6I%@%$%*%&!D(B4.0g,$BF|6I%+%s%>%&!D(B2.0g |
085 | $B%D%`%i?@HkEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$7$s$T$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B>.;y$<$s$=$/!"5$4I;Y$<$s$=$/!"5$4I;Y1j(B $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEY$"$k$$$O$=$l0J>e$N?M$G!"8F5[:$Fq$r $B#1!KSCB)!"31SV$rH<$&$,S=ab$N>/$J$$>l9g!#(B $B-#!VLt8z!&LtM}!W(B $B#1!%931j>I:nMQ!J%i%C%H!K(B $B#2!%:nMQ5!=x(B $B!!!J#1!K%m%$%3%H%j%(%s!J#L#T!K;:@8AK32:nMQ!J(Bin vitro$B!K(B $B!!!J#2!K931j>I:nMQ!J(Bin vitro$B!K(B |
$BF|6I%^%*%&!D(B5.0g,$BF|6I%-%g%&%K%s!D(B4.0g,$BF|6I%3%&%\%/!D(B3.0g,$BF|6I%A%s%T!D(B2.5g,$BF|6I%+%s%>%&!D(B2.0g,$BF|6I%5%$%3!D(B2.0g,$BF|6I%=%h%&!D(B1.5g |
086 | $B%D%`%iEv5"0{;R(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$H$&$-$$$s$7(B |
$B-!!V8zG=!&8z2L!W(B $BNd$(>I$N$b$N$NI!'K}@-<>?>(B($BJ,HgJ*$N>/$J$$$b$N(B)$B!"$+$f$_(B $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$NDc2<$7$??M$NHiIf<@45$G!"GBaZ$r $B#1!KHiIf$,4%Ag$7$F<>=a$7$F$$$J$$>l9g!#(B $B#2!KO7?M$KE,MQ$5$l$k$3$H$,B?$$!#(B |
$BF|6I%H%&%-!D(B5.0g,$BF|6I%8%*%&!D(B4.0g,$BF|6I%7%c%/%d%/!D(B3.0g,$BF|6I%;%s%-%e%&!D(B3.0g,$BF|6I%\%&%U%&!D(B3.0g,$BF|6I%*%&%.!D(B1.5g,$BF|6I%1%$%,%$!D(B1.5g,$BF|6I%+%s%>%&!D(B1.0g,$B%7%D%j%7!D(B3.0g,$B%+%7%e%&!D(B2.0g |
087 | $B%D%`%iO;L#4](B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$m$/$_$,$s(B |
$B-!!V8zG=!&8z2L!W(B $BHh$l$d$9$/$FG"NL8:>/$^$?$OB?G"$G!";~$K8}3i$N$"$k$b$N$NI(B:$BGSG":$Fq!"IQG"!"$`$/$_!"$+$f$_(B $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$NDc2<$7$??M$G!"9xDK$*$h$S2<;h$NC&NO46!"$7$S$l$J$I$,$"$j!"G"0UIQ?t!"GSG";~0cOB46$J$I$rAJ$($k>l9g$KMQ$$$k!#(B $B#1!KH,L#CO2+4]!"5m $B#2!K>eJ"It$KHf$Y$F2 $B#3!KHhO+7qBU46!"J"DK$J$I$rH<$&>l9g!#(B |
$BF|6I%8%*%&!D(B5.0g,$BF|6I%5%s%7%e%f!D(B3.0g,$BF|6I%5%s%d%/!D(B3.0g,$BF|6I%?%/%7%c!D(B3.0g,$BF|6I%V%/%j%g%&!D(B3.0g,$BF|6I%\%?%s%T!D(B3.0g |
088 | $B%D%`%iFs[2Er(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$K$8$e$D$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B8^==8*(B $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEY$N?M$G!"8*$d>eOS$,DK$`>l9g$KMQ$$$k!#(B |
$BF|6I%O%s%2!D(B4.0g,$BF|6I%=%&%8%e%D!D(B3.0g,$BF|6I%*%&%4%s!D(B2.5g,$BF|6I%3%&%V%7!D(B2.5g,$BF|6I%A%s%T!D(B2.5g,$BF|6I%S%c%/%8%e%D!D(B2.5g,$BF|6I%V%/%j%g%&!D(B2.5g,$BF|6I%+%s%>%&!D(B1.0g,$BF|6I%7%g%&%-%g%&!D(B1.0g,$B%$%l%$%;%s!D(B2.5g,$B%F%s%J%s%7%g%&!D(B2.5g,$B%o%-%g%&%+%D!D(B2.5g |
089 | $B%D%`%i<#BGKP0lJ}(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$8$@$\$/$$$C$]$&(B |
$B-!!V8zG=!&8z2L!W(B $BBGKP$K$h$k$O$l5Z$SDK$_(B $B-"!V;HMQL\I8!a>Z!W(B $BBGKP!"G1:CEy$G!"45It$, |
$BF|6I%1%$%R!D(B3.0g,$BF|6I%;%s%-%e%&!D(B3.0g,$BF|6I%;%s%3%D!D(B3.0g,$BF|6I%+%s%>%&!D(B1.5g,$BF|6I%@%$%*%&!D(B1.0g,$BF|6I%A%g%&%8!D(B1.0g,$B%\%/%=%/!D(B3.0g |
090 | $B%D%`%i@6GYEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$;$$$O$$$H$&(B |
$B-!!V8zG=!&8z2L!W(B $Bab$NB?$/=P$k31(B $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$NDc2<$7$??M$G!"G4cG$G@Z$l$K$/$$ab$,B?$/31SV$,A+1d2=$7$?>l9g$KMQ$$$k!#(B $B#1!K>e5->I>u$,D9$S$$$F0v9"DK!"SN@l9g!#(B $B#2!KK}@-2=$7$?8F5[4o<@45$Gab$NB?$/=P$k31!#(B $B-#!VLt8z!&LtM}!W(B $B#1!%5nab:nMQ!J%&%5%.!"%O%H!"(Bin vitro$B!K(B $B#2!%:nMQ5!=x(B $B!!!J#1!KG41U@~LSM"Aw7O$KBP$9$k:nMQ!J%&%5%.!"(Bin vitro$B!K(B $B!!!J#2!K3h@-;@AG!"%1%_%+%k%a%G%#%(!<%?!<$KBP$9$k:nMQ(B $B!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!J(Bin vitro$B!K(B |
$BF|6I%H%&%-!D(B3.0g,$BF|6I%P%/%b%s%I%&!D(B3.0g,$BF|6I%V%/%j%g%&!D(B3.0g,$BF|6I%*%&%4%s!D(B2.0g,$BF|6I%-%-%g%&!D(B2.0g,$BF|6I%-%g%&%K%s!D(B2.0g,$BF|6I%5%s%7%7!D(B2.0g,$BF|6I%=%&%O%/%R!D(B2.0g,$BF|6I%?%$%=%&!D(B2.0g,$BF|6I%A%s%T!D(B2.0g,$BF|6I%+%s%>%&!D(B1.0g,$BF|6I%4%_%7!D(B1.0g,$BF|6I%7%g%&%-%g%&!D(B1.0g,$B%A%/%8%g!D(B2.0g,$B%F%s%b%s%I%&!D(B2.0g,$B%P%$%b!D(B2.0g |
091 | $B%D%`%iC]G!29C@Er(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$A$/$8$g$&$s$?$s$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B%$%s%U%k%(%s%6!"Iw $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$NDc2<$7$??M$G!"46KA$J$I$GH/G.$,D9$S$-!"$"$k$$$O2rG.8e!"31$,=P$Fab$,B?$/!"ITL2$rAJ$($k>l9g$KMQ$$$k!#(B $B#1!K@:?@IT0B!"?4X)P6?J$J$I$rH<$&>l9g!#(B $B#2!K5(O>2 |
$BF|6I%O%s%2!D(B5.0g,$BF|6I%5%$%3!D(B3.0g,$BF|6I%P%/%b%s%I%&!D(B3.0g,$BF|6I%V%/%j%g%&!D(B3.0g,$BF|6I%-%-%g%&!D(B2.0g,$BF|6I%-%8%D!D(B2.0g,$BF|6I%3%&%V%7!D(B2.0g,$BF|6I%A%s%T!D(B2.0g,$BF|6I%*%&%l%s!D(B1.0g,$BF|6I%+%s%>%&!D(B1.0g,$BF|6I%7%g%&%-%g%&!D(B1.0g,$BF|6I%K%s%8%s!D(B1.0g,$B%A%/%8%g!D(B3.0g |
092 | $B%D%`%i<"1";jJuEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$8$$$s$7$[$&$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B5u $B-"!V;HMQL\I8!a>Z!W(B $BBNNO$,Dc2<$7$??M$NK}@-$K7P2a$7$?31SV$KMQ$$$k!#(B $B#1!KHf3SE*@Z$l$d$9$$ab$G!"NL$N$5$[$IB?$/$J$$>l9g!#(B $B#2!K?)M_IT?6!"A4?H7qBU46!"Ep4@$J$I$rH<$&>l9g!#(B $B#3!K8F5[4o<@45$,D9$S$$$?>l9g$N$;$-!&$?$s!#(B |
$BF|6I%3%&%V%7!D(B3.0g,$BF|6I%5%$%3!D(B3.0g,$BF|6I%7%c%/%d%/!D(B3.0g,$BF|6I%A%b!D(B3.0g,$BF|6I%A%s%T!D(B3.0g,$BF|6I%H%&%-!D(B3.0g,$BF|6I%P%/%b%s%I%&!D(B3.0g,$BF|6I%S%c%/%8%e%D!D(B3.0g,$BF|6I%V%/%j%g%&!D(B3.0g,$BF|6I%+%s%>%&!D(B1.0g,$BF|6I%O%C%+!D(B1.0g,$B%8%C%3%T!D(B3.0g,$B%P%$%b!D(B2.0g |
093 | $B%D%`%i<"1"9_2PEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$8$$$s$3$&$+$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B$N$I$K$&$k$*$$$,$J$/ab$N=P$J$/$F31$3$`$b$N(B $B-"!V;HMQL\I8!a>Z!W(B $BBNNODc2<$7$??M$G!"HiIf$N?'$,@u9u$/!"31SV!"G4cG$G@Z$l$K$/$$ab$J$I$N$"$k>l9g$KMQ$$$k!#(B $B#1!KM $B#2!KO7?M$d5u $B#3!K8F5[4o<@45$,D9$S$$$?>l9g!#(B |
$BF|6I%=%&%8%e%D!D(B3.0g,$BF|6I%8%*%&!D(B2.5g,$BF|6I%7%c%/%d%/!D(B2.5g,$BF|6I%A%s%T!D(B2.5g,$BF|6I%H%&%-!D(B2.5g,$BF|6I%P%/%b%s%I%&!D(B2.5g,$BF|6I%*%&%P%/!D(B1.5g,$BF|6I%+%s%>%&!D(B1.5g,$BF|6I%A%b!D(B1.5g,$B%F%s%b%s%I%&!D(B2.5g |
095 | $B%D%`%i8^8WEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$4$3$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B$;$-!"5$4I;Y$<$s$=$/(B $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$N$"$k?M$G!"SCLD!"7c$7$$31SV$N$"$k>l9g$KMQ$$$k!#(B $B#1!K0-46!"H/G.$O$J$/!"<+A3H/4@!"8}3i$rAJ$($k>l9g!#(B $B#2!K>.;y$KIQMQ$5$l$k!#(B |
$BF|6I%;%C%3%&!D(B10.0g,$BF|6I%-%g%&%K%s!D(B4.0g,$BF|6I%^%*%&!D(B4.0g,$BF|6I%=%&%O%/%R!D(B3.0g,$BF|6I%+%s%>%&!D(B2.0g |
096 | $B%D%`%i $B$5$$$\$/$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B5$J,$,$U$5$$$G!"0v9"!"?)F;It$K0[J*46$,$"$j!";~$KF0X)!"$a$^$$!"SR5$$J$I$rH<$&I(B:$B>.;y$<$s$=$/!"5$4I;Y$<$s$=$/!"5$4I;Y1j!"$;$-!"IT0B?@7P>I(B $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEY$N?M$G!"7ZEY$N6;OF6lK~!"?4c]It$NKDK~46$,$"$j!"31SV!"SCLD!"@:?@IT0B!"M^$&$D798~!"?)M_IT?6!"A4?H7qBU46$J$I$rAJ$($k>l9g$KMQ$$$k!#(B $B-#!VLt8z!&LtM}!W(B $B#1!%931j>I:nMQ!J%b%k%b%C%H!"(Bin vitro$B!K(B $B#2!%5$F;G4Kl@~LSM"Aw$N2~A1:nMQ!J(Bin vitro$B!K(B $B#3!%93IT0B:nMQ!J%^%&%9!K(B $B#4!%:nMQ5!=x(B $B!!!J#1!K%1%_%+%k%a%G%#%(!<%?!<$N;:@8!&M7N%M^@):nMQ!J(Bin vitro$B!!!!!!!!!!!K(B $B!!!J#2!K#I#g#E;:@8M^@):nMQ!J(Bin vitro$B!K(B $B!!!J#3!K%5%$%H%+%$%s;:@8$KBP$9$k:nMQ!J(Bin vitro$B!K(B $B!!!J#4!K9%;@5e$KBP$9$k:nMQ!J(Bin vitro$B!K(B $B!!!J#5!K#N#O;:@8$KBP$9$k:nMQ!J(Bin vitro$B!K(B $B!!!J#6!K@\CeJ,;RH/8=M^@):nMQ!J(Bin vitro$B!K(B $B!!!J#7!K%9%F%m%$%I |
$BF|6I%5%$%3!D(B7.0g,$BF|6I%O%s%2!D(B5.0g,$BF|6I%V%/%j%g%&!D(B5.0g,$BF|6I%*%&%4%s!D(B3.0g,$BF|6I%3%&%\%/!D(B3.0g,$BF|6I%?%$%=%&!D(B3.0g,$BF|6I%K%s%8%s!D(B3.0g,$BF|6I%+%s%>%&!D(B2.0g,$BF|6I%=%h%&!D(B2.0g,$BF|6I%7%g%&%-%g%&!D(B1.0g |
097 | $B%D%`%iBgKIIwEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$@$$$\$&$U$&$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B4X@a$,$O$l$FDK$_!"Kcac!"6/D>$7$F6~?-$7$,$?$$$b$N$NI(B:$B2<;h$NK}@-4X@a%j%&%^%A!"K}@-4X@a1j!"DKIw(B $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$NDc2<$7$??M$G!"4i?'$,0-$/!"4X@a$N |
$BF|6I%*%&%.!D(B3.0g,$BF|6I%8%*%&!D(B3.0g,$BF|6I%7%c%/%d%/!D(B3.0g,$BF|6I%=%&%8%e%D!D(B3.0g,$BF|6I%H%&%-!D(B3.0g,$BF|6I%\%&%U%&!D(B3.0g,$BF|6I%;%s%-%e%&!D(B2.0g,$BF|6I%+%s%>%&!D(B1.5g,$BF|6I%4%7%D!D(B1.5g,$BF|6I%?%$%=%&!D(B1.5g,$BF|6I%K%s%8%s!D(B1.5g,$B%-%g%&%+%D!D(B1.5g,$B%H%A%e%&!D(B3.0g,$B%+%s%-%g%&!D(B1.0g,$B=$<#%V%7Kv!D(B1.0g |
098 | $B%D%`%i2+fM7zCfEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$*$&$.$1$s$A$e$&$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B?HBN5u $B-"!V;HMQL\I8!a>Z!W(B $BBNNO$NDc2<$7$??M$G!"HhO+7qBU46$,Cx$7$/!"Ep4@$N$"$k>l9g$KMQ$$$k!#(B $B#1!KJ"DK!"?)M_IT?6!"B)@Z$l$J$I$rH<$&>l9g!#(B $B#2!KH/?>!"$S$i$s$J$I$NHiIf>I>u$rH<$&>l9g!#(B $B#3!KAO=}<#L~$NA+1d2=$dK}@-2=G?Ac$N$"$k>l9g!#(B $B#4!KJ"It$OJ"JI$,Gv$/J"D>6Z$,6[D%$7$F$$$k>l9g!#(B |
$BF|6I%7%c%/%d%/!D(B6.0g,$BF|6I%*%&%.!D(B4.0g,$BF|6I%1%$%R!D(B4.0g,$BF|6I%?%$%=%&!D(B4.0g,$BF|6I%+%s%>%&!D(B2.0g,$BF|6I%7%g%&%-%g%&!D(B1.0g |
099 | $B%D%`%i>.7zCfEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$7$g$&$1$s$A$e$&$H$&(B |
$B-!!V8zG=!&8z2L!W(B $BBN $B-"!V;HMQL\I8!a>Z!W(B $BBN $B#1!KJ"DK$rH<$&>l9g!#(B $B#2!K?4X)P6?J!"Ep4@!";M;h7qBU46$J$I$rH<$&>l9g!#(B $B#3!K5u |
$BF|6I%7%c%/%d%/!D(B6.0g,$BF|6I%1%$%R!D(B4.0g,$BF|6I%?%$%=%&!D(B4.0g,$BF|6I%+%s%>%&!D(B2.0g,$BF|6I%7%g%&%-%g%&!D(B1.0g |
100 | $B%D%`%iBg7zCfEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$@$$$1$s$A$e$&$H$&(B |
$B-!!V8zG=!&8z2L!W(B $BJ"$,Nd$($FDK$_!"J"ItKDK~46$N$"$k$b$N(B $B-"!V;HMQL\I8!a>Z!W(B $BBNNO$,Dc2<$7$??M$G;M;h$dJ"It$,Nd$(!"J"DK!"J"ItKDK~!"8]D2$N$"$k>l9g$KMQ$$$k!#(B $B#1!KJ"JI$,$&$9$/Fp $B#2!KNd$($K$h$j>I>u$N0-2=$9$k>l9g!#(B $B#3!K3+J"=Q8e$ND24IDL2a>c32$KH<$&J"DK!"J"ItKDK~46!#(B $B-#!VLt8z!&LtM}!W(B $B!L%R%H$G$N:nMQ!M(B $B!!#1!%>C2=4I1?F0B%?J:nMQ(B $B!!#2!%>C2=4I%[%k%b%s$KBP$9$k:nMQ(B $B!LF0J*$G$N:nMQ!M(B $B!!#1!%>C2=4I1?F0B%?J:nMQ!J%$%L!K(B $B!!#2!%%$%l%&%92~A1:nMQ!J%i%C%H!"%^%&%9!K(B $B!!#3!%>C2=4I5!G=0[>o2~A1:nMQ!J%i%C%H!K(B $B!!#4!%:nMQ5!=x(B $B!!!!!J#1!K>C2=4I1?F0B%?J:nMQ!J(Bin vitro$B!K(B $B!!!!!J#2!K%7%/%m%*%-%7%2%J!<% $B!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!J(Bin vitro$B!K(B |
$BF|6I%K%s%8%s!D(B3.0g,$BF|6I%5%s%7%g%&!D(B2.0g,$B%+%s%-%g%&!D(B5.0g |
101 | $B%D%`%i>#Kc3k:,Er(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$7$g$&$^$+$C$3$s$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B46KA$N=i4|!"HiIf1j(B $B-"!V;HMQL\I8!a>Z!W(B $B46KA$N=i4|!"HiIf1j$KMQ$$$k!#(B $B#1!KF,DK!"H/G.!"0-46$J$I$rH<$&>l9g!#(B $B#2!KKc?>$J$IH/?>$rH<$&>l9g!#(B |
$BF|6I%+%C%3%s!D(B5.0g,$BF|6I%7%c%/%d%/!D(B3.0g,$BF|6I%7%g%&%^!D(B2.0g,$BF|6I%+%s%>%&!D(B1.5g,$BF|6I%7%g%&%-%g%&!D(B0.5g |
102 | $B%D%`%iEv5"Er(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$H$&$-$H$&(B |
$B-!!V8zG=!&8z2L!W(B $BGXCf$K4(Nd$r3P$(!"J"ItKDK~46$dJ"DK$N$"$k$b$N(B $B-"!V;HMQL\I8!a>Z!W(B $BNd$(>I$G7l?'$N0-$$Hf3SE*BNNO$NDc2<$7$??M$G!"6;J"It(B $B$h$jGXIt$K$+$1$F!"aVDK$rAJ$($k>l9g$KMQ$$$k!#(B $B#1!K69?4>IMM!"O>4V?@7PDKMM$NDK$_$,$"$k>l9g!#(B |
$BF|6I%H%&%-!D(B5.0g,$BF|6I%O%s%2!D(B5.0g,$BF|6I%1%$%R!D(B3.0g,$BF|6I%3%&%\%/!D(B3.0g,$BF|6I%7%c%/%d%/!D(B3.0g,$BF|6I%K%s%8%s!D(B3.0g,$BF|6I%*%&%.!D(B1.5g,$BF|6I%5%s%7%g%&!D(B1.5g,$BF|6I%+%s%>%&!D(B1.0g,$B%+%s%-%g%&!D(B1.5g |
103 | $B%D%`%i;@\'?NEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$5$s$=$&$K$s$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B?4?H$,$D$+$l $B-"!V;HMQL\I8!a>Z!W(B $BBNNO$NDc2<$7$??M$G!"?4?H$H$b$KHhO+$7$F!"ITL2$rAJ$($k>l9g$KMQ$$$k!#(B $B#1!KK}@-<@4545 $B#2!K@:?@IT0B!"?@7P2aIR$J$I$rH<$&>l9g!#(B |
$BF|6I%V%/%j%g%&!D(B5.0g,$BF|6I%;%s%-%e%&!D(B3.0g,$BF|6I%A%b!D(B3.0g,$BF|6I%+%s%>%&!D(B1.0g,$B%5%s%=%&%K%s!D(B10.0g |
104 | $B%D%`%i?I0P@6GYEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$7$s$$$;$$$O$$$H$&(B |
$B-!!V8zG=!&8z2L!W(B $BI!$E$^$j!"K}@-I!1j!"C_G?>I(B $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEY$"$k$$$O$=$l0J>e$N?M$G!"G?@-I!O3!"8eI!O3$J$I$rH<$&I!<@45$KMQ$$$k!#(B $B#1!K45It$KG.465Z$SaVDK$rH<$&>l9g!#(B $B-#!VLt8z!&LtM}!W(B $B:nMQ5!=x(B $B!!!!931j>I:nMQ!J(Bin vitro$B!K(B |
$BF|6I%;%C%3%&!D(B5.0g,$BF|6I%P%/%b%s%I%&!D(B5.0g,$BF|6I%*%&%4%s!D(B3.0g,$BF|6I%5%s%7%7!D(B3.0g,$BF|6I%A%b!D(B3.0g,$BF|6I%7%g%&%^!D(B1.0g,$B%S%c%/%4%&!D(B3.0g,$B%7%s%$!D(B2.0g,$B%S%o%h%&!D(B2.0g, |
105 | $B%D%`%iDLF3;6(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$D$&$I$&$5$s(B |
$B-!!V8zG=!&8z2L!W(B $BHf3SE*BNNO$,$"$j2 $B-"!V;HMQL\I8!a>Z!W(B $BBN3J!"BNNO$H$b$K=<l9g$KMQ$$$k!#(B $B#1!KEm3K>55$Er$KHf$Y!"@:?@?@7P>I>u$,$h$j7c$7$$>l9g!#(B $B#2!KF,DK!"$N$\$;!"ITL2!"IT0B$J$I$N@:?@?@7P>I>u$rH<$&>l9g!#(B $B#3!K7n7PIT=g!"7n7P:$Fq>I$J$I$N$"$kIX?M!#(B |
$BF|6I%-%8%D!D(B3.0g,$BF|6I%@%$%*%&!D(B3.0g,$BF|6I%H%&%-!D(B3.0g,$BF|6I%+%s%>%&!D(B2.0g,$BF|6I%3%&%+!D(B2.0g,$BF|6I%3%&%\%/!D(B2.0g,$BF|6I%A%s%T!D(B2.0g,$BF|6I%b%/%D%&!D(B2.0g,$B%=%\%/!D(B2.0g,$BL5?e%\%&%7%g%&!D(B1.8g |
106 | $B%D%`%i297PEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$&$s$1$$$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$NDc2<$7$?Nd$(>I$N?M$G!" $B#1!K@-4o=P7l!"7n7P0[>o!"ITG%$J$I$N$"$kIX?M!#(B $B#2!K>e5->I>u$O!"@-<~4|$K4XO"$7$F>CD9$9$k$3$H$,B?$$!#(B $B-#!VLt8z!&LtM}!W(B $B#1!%GSMqM6H/:nMQ!J%i%C%H!K(B $B#2!%:nMQ5!=x(B $B!!!!!!!!%[%k%b%s$KBP$9$k:nMQ!J%i%C%H!"(Bin vitro$B!K(B |
$BF|6I%P%/%b%s%I%&!D(B4.0g,$BF|6I%O%s%2!D(B4.0g,$BF|6I%H%&%-!D(B3.0g,$BF|6I%+%s%>%&!D(B2.0g,$BF|6I%1%$%R!D(B2.0g,$BF|6I%7%c%/%d%/!D(B2.0g,$BF|6I%;%s%-%e%&!D(B2.0g,$BF|6I%K%s%8%s!D(B2.0g,$BF|6I%\%?%s%T!D(B2.0g,$BF|6I%4%7%e%f!D(B1.0g,$BF|6I%7%g%&%-%g%&!D(B1.0g,$B%"%-%g%&!D(B2.0g |
107 | $B%D%`%i5m $B$4$7$c$8$s$-$,$s(B |
$B-!!V8zG=!&8z2L!W(B $BHh$l$d$9$/$F!";M;h$,Nd$($d$9$/G"NL8:>/$^$?$OB?G"$G;~$K8}3i$,$"$kI(B:$B2<;hDK!"9xDK!"$7$S$l!"O7?M$N$+$9$_L\!"$+$f$_!"GSG":$Fq!"IQG"!"$`$/$_(B $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$NDc2<$7$??M$"$k$$$OO7?M$G9xIt$*$h$S2<;h$NC&NO46!"Nd$(!"$7$S$l$J$I$,$"$j!"GSG"$N0[>o!JFC$KLk4V$NIQG"!K$rAJ$($k>l9g$KMQ$$$k!#(B $B#1!K>eJ"It$K$/$i$Y$F2 $B#3!KHhO+7qBU46!"9xDK!"8}3i$J$I$rH<$&>l9g!#(B $B-#!VLt8z!&LtM}!W(B $B#1!%?e>=BN:.By$KBP$9$k:nMQ!J%i%C%H!K(B $B#2!%?@7PEAF3B.EY$KBP$9$k:nMQ!J%i%C%H!K(B $B#3!%93?/32 $B#5!%:nMQ5!=x(B $B!!#1!K?e>=BN:.By$KBP$9$k:nMQ!J(Bin vitro$B!K(B $B!!#2!K93?/32 |
$BF|6I%8%*%&!D(B5.0g,$BF|6I%4%7%D!D(B3.0g,$BF|6I%5%s%7%e%f!D(B3.0g,$BF|6I%5%s%d%/!D(B3.0g,$BF|6I%7%c%<%s%7!D(B3.0g,$BF|6I%?%/%7%c!D(B3.0g,$BF|6I%V%/%j%g%&!D(B3.0g,$BF|6I%\%?%s%T!D(B3.0g,$BF|6I%1%$%R!D(B1.0g,$B=$<#%V%7Kv!D(B1.0g |
108 | $B%D%`%i?M;2M\1IEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$K$s$8$s$h$&$($$$H$&(B |
$B-!!V8zG=!&8z2L!W(B $BIB8e$NBNNODc2 $B-"!V;HMQL\I8!a>Z!W(B $BIB8e!&=Q8e$"$k$$$OK}@-<@45$J$I$GHhO+?j $B#1!KA4?H7qBU46!"4i?'ITNI!"?)M_IT?6$J$I$rH<$&$3$H$,B?$$!#(B $B#2!KK}@-<@45$G!"HyG.!"0-46!"31SV$J$I$rH<$&>l9g!#(B |
$BF|6I%8%*%&!D(B4.0g,$BF|6I%H%&%-!D(B4.0g,$BF|6I%S%c%/%8%e%D!D(B4.0g,$BF|6I%V%/%j%g%&!D(B4.0g,$BF|6I%K%s%8%s!D(B3.0g,$BF|6I%1%$%R!D(B2.5g,$BF|6I%*%s%8!D(B2.0g,$BF|6I%7%c%/%d%/!D(B2.0g,$BF|6I%A%s%T!D(B2.0g,$BF|6I%*%&%.!D(B1.5g,$BF|6I%+%s%>%&!D(B1.0g,$BF|6I%4%_%7!D(B1.0g |
109 | $B%D%`%i>. $B$7$g$&$5$$$3$H$&$+$-$-$g$&$;$C$3$&(B |
$B-!!V8zG=!&8z2L!W(B $B0v9"$,$O$l$FDK$`I!'Y(Em1j!"Y(Em<~0O1j(B $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEY$N?M$G!"HyG.$,$"$j!"?4c]It$h$j5(O>It$K$+$1$F$N6lK~46!"05Gw46!J6;OF6lK~!K!"?)M_IT?6$J$I$rAJ$($k>l9g$KMQ$$$k!#(B $B#1!K>e5$F;$N0!5^@-$J$$$7K}@-$N1j>I@-<@45!#(B |
$BF|6I%;%C%3%&!D(B10.0g,$BF|6I%5%$%3!D(B7.0g,$BF|6I%O%s%2!D(B5.0g,$BF|6I%*%&%4%s!D(B3.0g,$BF|6I%-%-%g%&!D(B3.0g,$BF|6I%?%$%=%&!D(B3.0g,$BF|6I%K%s%8%s!D(B3.0g,$BF|6I%+%s%>%&!D(B2.0g,$BF|6I%7%g%&%-%g%&!D(B1.0g |
110 | $B%D%`%iN)8z;6(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$j$C$3$&$5$s(B |
$B-!!V8zG=!&8z2L!W(B $BH4;u8e$NaVDK!";uDK(B $B-"!V;HMQL\I8!a>Z!W(B $B;uDK!";u:,DK$*$h$S8}9PFb$N |
$BF|6I%5%$%7%s!D(B2.0g,$BF|6I%7%g%&%^!D(B2.0g,$BF|6I%\%&%U%&!D(B2.0g,$BF|6I%+%s%>%&!D(B1.5g,$BF|6I%j%e%&%?%s!D(B1.0g |
111 | $B%D%`%i@6?4O!;R0{(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$;$$$7$s$l$s$7$$$s(B |
$B-!!V8zG=!&8z2L!W(B $BA4?H7qBU46$,$"$j!"8}$d@e$,4%$-!"G"$,=P$7$V$k$b$N$NI(B:$B;DG"46!"IQG"!"GSG"DK(B $B-"!V;HMQL\I8!a>Z!W(B $BJ?AG$h$j0_D25u $B#1!KNd$(>I$G?@7P $B#2!KK}@-$NHgG"4o<@45$KH<$&>l9g!#(B |
$BF|6I%P%/%b%s%I%&!D(B4.0g,$BF|6I%V%/%j%g%&!D(B4.0g,$BF|6I%*%&%4%s!D(B3.0g,$BF|6I%7%c%<%s%7!D(B3.0g,$BF|6I%K%s%8%s!D(B3.0g,$BF|6I%*%&%.!D(B2.0g,$BF|6I%+%s%>%&!D(B1.5g,$B%l%s%K%/!D(B4.0g,$B%8%3%C%T!D(B2.0g |
112 | $B%D%`%iCvNjEr9g;MJ*Er(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$A$g$l$$$H$&$4$&$7$b$D$H$&(B |
$B-!!V8zG=!&8z2L!W(B $BHiIf$,8OAg$7!"?'$D$d$N0-$$BNc32$N$J$$?M$NI(B:$BGSG":$Fq!"GSG"DK!";DG"46!"IQG"(B $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEYA08e$N?M$G!"IQG"!";DG"46!"GSG"DK$J$I$NGSG">c32$,K}@-2=$7$?$j!"H?I|$7$F5/$3$k>l9g$KMQ$$$k!#(B |
$BF|6I%8%*%&!D(B3.0g,$BF|6I%7%c%/%d%/!D(B3.0g,$BF|6I%;%s%-%e%&!D(B3.0g,$BF|6I%?%/%7%c!D(B3.0g,$BF|6I%A%g%l%$!D(B3.0g,$BF|6I%H%&%-!D(B3.0g,$BF|6I%V%/%j%g%&!D(B3.0g,$B%"%-%g%&!D(B3.0g,$B%+%C%;%-!D(B3.0g |
113 | $B%D%`%i;02+_C?4Er(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$5$s$*$&$7$c$7$s$H$&(B |
$B-!!V8zG=!&8z2L!W(B $BHf3SE*BNNO$,$"$j!"$N$\$;5$L#$G!"4iLL9HD,$7!"@:?@IT0B$G!"JXHk$N798~$N$"$k$b$N$NI(B:$B9b7l05$N?oH<>I>u(B($B$N$\$;!"8*$3$j!"<*$J$j!"F,=E!"ITL2!"IT0B(B)$B!"I!7l!"<&=P7l!"JXHk!"99G/4|=}32!"7l$NF;>I(B $B-"!V;HMQL\I8!a>Z!W(B $BBN3J!&BNNO$H$b$K=<l9g$KMQ$$$k!#(B $B#1!K5$J,$,$$$i$$$i$7$FMn$ACe$+$:!"@:?@IT0B$dITL2$rAJ$($k>l9g!#(B $B#2!K?4c]It$NKDK~46$rAJ$($k>l9g!#(B $B#3!KI!=P7l!"2<7l$J$I$N$"$k>l9g!#$?$@$7!"=P7l$,D9$S$$$FIO7l$NCx$7$$>l9g$K$OMQ$$$J$$!#(B $B-#!VLt8z!&LtM}!W(B $B:nMQ5!=x(B $B!!!!#1!%7l059_2<:nMQ!J(Bin vitro$B!K(B $B!!!!#2!%Cf?u?@7P7O$KBP$9$k:nMQ!J(Bin vitro$B!K(B |
$BF|6I%*%&%4%s!D(B3.0g,$BF|6I%*%&%l%s!D(B3.0g,$BF|6I%@%$%*%&!D(B3.0g |
114 | $B%D%`%i $B$5$$$l$$$H$&(B |
$B-!!V8zG=!&8z2L!W(B $BEG$-5$!"?)M_IT?6!"$N$I$N$+$o$-!"GSG"$,>/$J$$$J$I$NI!'?e_C@-2 $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEY$N?M$G!"?4c]It$h$j5(O>It$K$+$1$F$N6lK~46!"$J$i$S$KDq93!&05DK!J6;OF6lK~!K$,$"$j!"G"NL8:>/!"Ib l9g$KMQ$$$k!#(B |
$BF|6I%5%$%3!D(B7.0g,$BF|6I%?%/%7%c!D(B5.0g,$BF|6I%O%s%2!D(B5.0g,$BF|6I%*%&%4%s!D(B3.0g,$BF|6I%=%&%8%e%D!D(B3.0g,$BF|6I%?%$%=%&!D(B3.0g,$BF|6I%A%g%l%$!D(B3.0g,$BF|6I%K%s%8%s!D(B3.0g,$BF|6I%V%/%j%g%&!D(B3.0g,$BF|6I%+%s%>%&!D(B2.0g,$BF|6I%1%$%R!D(B2.0g,$BF|6I%7%g%&%-%g%&!D(B1.0g |
115 | $B%D%`%i0_NjEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$$$l$$$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B?e_C@-$N2 $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEY$N?M$G!"?4c]It$K?6?e2;$rG'$a!"?eMM@-$N2 $B#1!KJ"ItKDK~46!"7ZEY$NJ"DK!"G"NL8:>/$J$I$rH<$&>l9g!#(B |
$BF|6I%3%&%\%/!D(B2.5g,$BF|6I%=%&%8%e%D!D(B2.5g,$BF|6I%?%/%7%c!D(B2.5g,$BF|6I%A%g%l%$!D(B2.5g,$BF|6I%A%s%T!D(B2.5g,$BF|6I%S%c%/%8%e%D!D(B2.5g,$BF|6I%V%/%j%g%&!D(B2.5g,$BF|6I%1%$%R!D(B2.0g,$BF|6I%7%g%&%-%g%&!D(B1.5g,$BF|6I%?%$%=%&!D(B1.5g,$BF|6I%+%s%>%&!D(B1.0g |
116 | $B%D%`%ih*Nj0{9gH>2F8|KQEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$V$/$j$g$&$$$s$4$&$O$s$2$3$&$\$/$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B5$J,$,$U$5$$$G!"0v9"!"?)F;It$K0[J*46$,$"$j!";~$KF0X)!"$a$^$$!"SR5$!"6;$d$1$J$I$,$"$j!"G"NL$N8:>/$9$k$b$N$NI(B:$BIT0B?@7P>I!"?@7P@-0_1j!"$D$o$j!"N/0{!"0_1j(B $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEY$"$k$$$O$d$dDc2<$7$??M$G!"M^$&$D>uBV$rDh$7!"0v9"It$N0[J*46!"0_ItKDK~46$rAJ$($k>l9g$KMQ$$$k!#(B $B#1!K$a$^$$!"F0X)!"0-?4!"?4c]It?6?e2;$J$I$rH<$&>l9g!#(B |
$BF|6I%O%s%2!D(B6.0g,$BF|6I%V%/%j%g%&!D(B5.0g,$BF|6I%=%&%8%e%D!D(B4.0g,$BF|6I%3%&%\%/!D(B3.0g,$BF|6I%A%s%T!D(B3.0g,$BF|6I%K%s%8%s!D(B3.0g,$BF|6I%=%h%&!D(B2.0g,$BF|6I%-%8%D!D(B1.5g,$BF|6I%7%g%&%-%g%&!D(B1.0g$B!!(B |
117 | $B%D%`%ih!DD8^Nj;6(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$$$s$A$s$4$l$$$5$s(B |
$B-!!V8zG=!&8z2L!W(B $B$N$I$,3i$$$F!"G"$,>/$J$$$b$N$NI(B:$BSREG!"$8$s$^$7$s!"FsF|?l$N$`$+$D$-!"$`$/$_(B $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEY$N?M$G!"8}3i!"G"NL8:>/!"Ib l9g$KMQ$$$k!#(B |
$BF|6I%?%/%7%c!D(B6.0g,$BF|6I%=%&%8%e%D!D(B4.5g,$BF|6I%A%g%l%$!D(B4.5g,$BF|6I%V%/%j%g%&!D(B4.5g,$BF|6I%1%$%R!D(B2.5g,$B%$%s%A%s%3%&!D(B4.0g |
118 | $B%D%`%iNjU*[24EEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$j$g$&$-$g$&$8$e$D$+$s$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B9x$KNd$($HDK$_$,$"$C$F!"G"NL$,B?$$I(B:$B9xDK!"9x$NNd$(!"LkG">I(B $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$,Dc2<$7$??M$G!"9xIt$h$j2<;h$K$+$1$F$NNd$($,82Cx$G!"IQG"$rAJ$($k>l9g$KMQ$$$k!#(B $B#1!KNd$($N$?$a$K9x2<;h$KaVDK$rAJ$($k$3$H$b$"$k!#(B |
$BF|6I%V%/%j%g%&!D(B6.0g,$BF|6I%S%c%/%8%e%D!D(B3.0g,$BF|6I%+%s%>%&!D(B2.0g,$B%+%s%-%g%&!D(B3.0g |
119 | $B%D%`%iNj4EU*L#?I2F?NEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$j$g$&$+$s$-$g$&$_$7$s$2$K$s$H$&(B |
$B-!!V8zG=!&8z2L!W(B $BIO7l!"Nd$(>I$GSCLD$rH<$&S=ab$NB?$$31SV2j$"$k$b$N!#5$4I;Y1j!"5$4I;YSCB)!"?4B!?j $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$,Dc2<$7!"Nd$(>I$GIO7l798~$K$"$k?M$N!"SCLD!"31SV!"S=ab!"?eMM@-I!=A$J$I$rDh$9$k>l9g$KMQ$$$k!#(B $B#1!K0_D25u $B#2!KHhO+7qBU46!"F0X)!"B)@Z$l!"Ib l9g!#(B |
$BF|6I%-%g%&%K%s!D(B4.0g,$BF|6I%O%s%2!D(B4.0g,$BF|6I%V%/%j%g%&!D(B4.0g,$BF|6I%4%_%7!D(B3.0g,$BF|6I%+%s%>%&!D(B2.0g,$BF|6I%5%$%7%s!D(B2.0g,$B%+%s%-%g%&!D(B2.0g |
120 | $B%D%`%i2+O"Er(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$*$&$l$s$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B0_It$NDdBZ46$d=E0546!"?)M_IT?6$N$"$k$b$N$NI(B:$B5^@-0_1j!"FsF|?l!"8}Fb1j(B $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEY0J>e$N?M$G!">eJ"ItDK!"0-?4!"SREG$,$"$j!"?4c]It$KDq93$NG'$a$i$l$k>l9g$KMQ$$$k!#(B $B#1!K?4c]It$NDdBZ46$d=E0546!"?)M_IT?6$J$I$rH<$&>l9g!#(B $B#2!K@e$K2+?'B]!"Kt$OGrB]$,$"$j!"8}=-$rH<$&>l9g!#(B |
$BF|6I%O%s%2!D(B6.0g,$BF|6I%*%&%l%s!D(B3.0g,$BF|6I%+%s%>%&!D(B3.0g,$BF|6I%1%$%R!D(B3.0g,$BF|6I%?%$%=%&!D(B3.0g,$BF|6I%K%s%8%s!D(B3.0g,$B%+%s%-%g%&!D(B3.0g |
121 | $B%D%`%i;0J*2+:#Er(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$5$s$b$D$*$&$4$s$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEY$"$k$$$O$=$l0J>e$N?M$G!" $B#1!K $B#2!K8}3i$rH<$&>l9g!#(B $B#3!K |
$BF|6I%8%*%&!D(B6.0g,$BF|6I%*%&%4%s!D(B3.0g,$BF|6I%/%8%s!D(B3.0g |
122 | $B%D%`%iGSG?;65ZEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$O$$$N$&$5$s$-$e$&$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B45It$,H/@V!" I(B |
$BF|6I%-%-%g%&!D(B4.0g,$BF|6I%+%s%>%&!D(B3.0g,$BF|6I%-%8%D!D(B3.0g,$BF|6I%7%c%/%d%/!D(B3.0g,$BF|6I%?%$%=%&!D(B3.0g,$BF|6I%7%g%&%-%g%&!D(B1.0g |
123 | $B%D%`%iEv5"7zCfEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$H$&$-$1$s$A$e$&$H$&(B |
$B-!!V8zG=!&8z2L!W(B $BHhO+$7$d$9$/!"7l?'$N$9$0$l$J$$$b$N$NI(B:$B7n7PDK!"2 $B-"!V;HMQL\I8!a>Z!W(B $BBNNO$NDc2<$7$??M$G!"HhO+$7$d$9$/!"4i?'ITNI!" $B#1!K@-4o=P7l!"<&=P7l$J$I$rH<$&>l9g!#(B $B#2!KJ"It$,Fp $B#3!K |
$BF|6I%7%c%/%d%/!D(B5.0g,$BF|6I%1%$%R!D(B4.0g,$BF|6I%?%$%=%&!D(B4.0g,$BF|6I%H%&%-!D(B4.0g,$BF|6I%+%s%>%&!D(B2.0g,$BF|6I%7%g%&%-%g%&!D(B1.0g |
124 | $B%D%`%i@n5]CcD4;6(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$;$s$-$e$&$A$c$A$g$&$5$s(B |
$B-!!V8zG=!&8z2L!W(B $B$+$I!"F,DK(B $B-"!V;HMQL\I8!a>Z!W(B $BBNNO$N6/ |
$BF|6I%3%&%V%7!D(B4.0g,$BF|6I%;%s%-%e%&!D(B3.0g,$BF|6I%1%$%,%$!D(B2.0g,$BF|6I%O%C%+!D(B2.0g,$BF|6I%S%c%/%7!D(B2.0g,$BF|6I%\%&%U%&!D(B2.0g,$BF|6I%+%s%>%&!D(B1.5g,$B%-%g%&%+%D!D(B2.0g,$B%A%c%h%&!D(B1.5g |
125 | $B%D%`%i7K;^h*Nj4]2C0Ugo?N(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$1$$$7$V$/$j$g$&$,$s$+$h$/$$$K$s(B |
$B-!!V8zG=!&8z2L!W(B $BHf3SE*BNNO$,$"$j!";~$K2 $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEY$b$7$/$O$=$l0J>e$N?M$G!"$N$\$;$F@V$i4i$N$3$H$,B?$/!"2 $B#1!KH)$N$"$l!"4NHC!":Bal!"aOlT$J$I$NHiIf>I>u$rH<$&>l9g!#(B $B#2!KF,DK!"8*$3$j!"$a$^$$!"$N$\$;!"B-$NNd$($J$I$rH<$&>l9g!#(B $B#3!KL57n7P!"2aB?7n7P!"7n7P:$Fq>I$J$I$N7n7P0[>o$N$"$kIX?M!#(B |
$BF|6I%h%/%$%K%s!D(B10.0g,$BF|6I%1%$%R!D(B4.0g,$BF|6I%7%c%/%d%/!D(B4.0g,$BF|6I%H%&%K%s!D(B4.0g,$BF|6I%V%/%j%g%&!D(B4.0g,$BF|6I%\%?%s%T!D(B4.0g |
126 | $B%D%`%iKc;R?N4](B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$^$7$K$s$,$s(B |
$B-!!V8zG=!&8z2L!W(B $BJXHk(B $B-"!V;HMQL\I8!a>Z!W(B $BBNNOCfEyEY$"$k$$$O$d$dDc2<$7$??M$N=,47@-JXHk$G!"O7?M$dIB8e$N5u |
$BF|6I%@%$%*%&!D(B4.0g,$BF|6I%-%8%D!D(B2.0g,$BF|6I%-%g%&%K%s!D(B2.0g,$BF|6I%3%&%\%/!D(B2.0g,$BF|6I%7%c%/%d%/!D(B2.0g,$B%^%7%K%s!D(B5.0g |
127 | $B%D%`%iKc2+Im;R:Y?IEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$^$*$&$V$7$5$$$7$s$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B0-4(!"HyG.!"A4?H7qBU!"Dc7l05$GF,DK!"$a$^$$$,$"$j!";M;h$KaVDKNd46$"$k$b$N$NI(B:$B46KA!"5$4I;Y1j!#(B $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$NDc2<$7$??M$N0-4($rH<$&H/G.!JHyG.!K$rL\I8$KMQ$$$k!#L.$OD@$s$G:Y$/!"NO$,$J$$$3$H$,B?$$!#O7?M$d5u $B#2!KF,DK!"31SV!"$N$I$NDK$_!"%/%7%c%_!"?eMM@-I!=A!" $B-#!VLt8z!&LtM}!W(B $B#1!%931j>I:nMQ!J%i%C%H!"%^%&%9!K(B $B#2!%93?/32 $B!!!!!!93?/32 |
$BF|6I%^%*%&!D(B4.0g,$BF|6I%5%$%7%s!D(B3.0g,$B=$<#%V%7Kv!D(B1.0g |
128 | $B%D%`%i7 $B$1$$$R$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B$d$;$F!"4i?'$,0-$/!"?)M_$,$J$/!"2 $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$NDc2<$7$F$$$k?M$N2 $B#1!K?)M_IT?6!"SREG!"J"DK$J$I$rH<$&>l9g!#(B $B#2!KJ"It$,Fp |
$BF|6I%=%&%8%e%D!D(B4.0g,$BF|6I%V%/%j%g%&!D(B4.0g,$BF|6I%5%s%d%/!D(B3.0g,$BF|6I%K%s%8%s!D(B3.0g,$BF|6I%?%/%7%c!D(B2.0g,$BF|6I%A%s%T!D(B2.0g,$BF|6I%+%s%>%&!D(B1.0g,$B%l%s%K%/!D(B3.0g,$B%5%s%6%7!D(B2.0g |
133 | $B%D%`%iBg>55$Er(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$@$$$8$g$&$-$H$&(B |
$B-!8zG=!&8z2L!W(B $BJ"It$,$+$?$/$D$+$($F!"JXHk$9$k$b$N!"$"$k$$$OHnK~BNo=,JXHk!"5^@-JXHk!"9b7l05!"?@7P>I!"?)Ev$j(B $B-"!V;HMQL\I8!a>Z!W(B $BBNNO$N=<l9g$KMQ$$$k!#(B $B#1!KIT0B!"ITL2!"6=J3$J$I$N@:?@>I>u$rH<$&>l9g!#(B |
$BF|6I%3%&%\%/!D(B5.0g,$BF|6I%-%8%D!D(B3.0g,$BF|6I%@%$%*%&!D(B2.0g,$BL5?e%\%&%7%g%&!D(B1.3g |
134 | $B%D%`%i7K;^2CgiLtBg2+Er(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$1$$$7$+$7$c$/$d$/$@$$$*$&$H$&(B |
$B-!!V8zG=!&8z2L!W(B $BHf3SE*BNNO$N$J$$?M$G!"J"ItKDK~$7!"D2Fb$NDdBZ46$"$k$$$OJ"DK$J$I$rH<$&$b$N$NI(B: 1.$B5^@-D21j!"BgD2%+%?%k(B 2.$B>o=,JXHk!"=IJX!"$7$V$jJ"(B $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$NDc2<$7$??M$G!"J"ItKDK~$7!"J"DK$,$"$j!"N"5^8e=E$rH<$&2 $B#1!KJX0U$r:E$9$,!"2w$/GSJX$7$J$$>l9g!#(B $B#2!K2<:^I~MQ8e$NJ"DK!#(B $B#3!K3+J"=Q8e$KJX$N2wDL$7$J$$>l9g!#(B |
$BF|6I%7%c%/%d%/!D(B6.0g,$BF|6I%1%$%R!D(B4.0g,$BF|6I%?%$%=%&!D(B4.0g,$BF|6I%+%s%>%&!D(B2.0g,$BF|6I%@%$%*%&!D(B2.0g,$BF|6I%7%g%&%-%g%&!D(B1.0g |
135 | $B%D%`%ih!DDhfEr(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$$$s$A$s$3$&$H$&(B |
$B-!!V8zG=!&8z2L!W(B $BG"NL8:>/!"$d!5JXHk$,$A$GHf3SE*BNNO$N$"$k$b$N$NI(B:$B2+aU!"4N9EJQ>I!"%M%U%m!<% $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$N$"$k?M$G!">eJ"It$h$j6;It$K$+$1$F$NKDK~46!"IT2w46$rAJ$(!"0-?4!"JXHk$rH<$&>l9g$KMQ$$$k!#(B $B#1!K2+aU$N$"$k>l9g!#(B $B#2!K8}3i!"G"NL8:>/!"HiIfGBaZ46$J$I$rH<$&>l9g!#(B $B-#!VLt8z!&LtM}!W(B $B#1!%4N>c32$KBP$9$k:nMQ!J%i%C%H!"%^%&%9!K(B $B#2!%MxC@:nMQ!J%i%C%H!K(B $B#3!%:nMQ5!=x!!(B $B!!!!!!!!4N>c32$KBP$9$k:nMQ!J(Bin vitro$B!K(B |
$BF|6I%5%s%7%7!D(B3.0g,$BF|6I%@%$%*%&!D(B1.0g,$B%$%s%A%s%3%&!D(B4.0g |
136 | $B%D%`%i@6=k1W5$Er(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$;$$$7$g$($C$-$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B=k5$$"$?$j!"=k$5$K$h$k?)M_IT?6!&2 $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$NDc2<$7$??M$G!"?)M_IT?6!"A4?H7qBU46$rAJ$($k>l9g$KMQ$$$k!#(B $B#1!KFpJX!"G"NL8:>/!"<+A3H/4@!" $B#2!K$$$o$f$k2F$d$;!"2F$^$1$KB?MQ$5$l$k!#(B |
$BF|6I%=%&%8%e%D!D(B3.5g,$BF|6I%K%s%8%s!D(B3.5g,$BF|6I%P%/%b%s%I%&!D(B3.5g,$BF|6I%*%&%.!D(B3.0g,$BF|6I%A%s%T!D(B3.0g,$BF|6I%H%&%-!D(B3.0g,$BF|6I%*%&%P%/!D(B1.0g,$BF|6I%+%s%>%&!D(B1.0g,$BF|6I%4%_%7!D(B1.0g |
137 | $B%D%`%i2CL#5"g#Er(B $B%(%-%9pyN3(B($B0eNEMQ(B) $B$+$_$-$R$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B5u $B-"!V;HMQL\I8!a>Z!W(B $BBN $B#1!K2<7l!"EG7l!"I!=P7l$J$I$rH<$&>l9g!#(B $B#2!KEp4@!"A4?H7qBU46!"?)M_IT?6$J$I$rH<$&>l9g!#(B $B-#!VLt8z!&LtM}!W(B $B93IT0B:nMQ!J%^%&%9!K(B |
$BF|6I%*%&%.!D(B3.0g,$BF|6I%5%$%3!D(B3.0g,$BF|6I%=%&%8%e%D!D(B3.0g,$BF|6I%K%s%8%s!D(B3.0g,$BF|6I%V%/%j%g%&!D(B3.0g,$BF|6I%*%s%8!D(B2.0g,$BF|6I%5%s%7%7!D(B2.0g,$BF|6I%?%$%=%&!D(B2.0g,$BF|6I%H%&%-!D(B2.0g,$BF|6I%+%s%>%&!D(B1.0g,$BF|6I%7%g%&%-%g%&!D(B1.0g,$BF|6I%b%C%3%&!D(B1.0g,$B%5%s%=%&%K%s!D(B3.0g,$B%j%e%&%,%s%K%/!D(B3.0g |
138 | $B%D%`%i5K9 $B$-$-$g$&$H$&(B |
$B-!!V8zG=!&8z2L!W(B $B0v9"$,$O$l$FDK$`I(B:$BY(Em1j!"Y(Em<~0O1j(B $B-"!V;HMQL\I8!a>Z!W(B $B0v!&9"It$N1j>I$G!"aVDK!" $B#1!K7ZEY$NH/G.!"31SV!"S=ab!"Sk2<:$Fq$J$I$rH<$&$3$H$,B?$$!#(B |
$BF|6I%+%s%>%&!D(B3.0g,$BF|6I%-%-%g%&!D(B2.0g |
3020 | $B%D%`%i$N@8Lt(B $B%3%&%8%sKv(B($BD4:^MQ(B) |
$B-!!V8zG=!&8z2L!W(B $B4AJ}=hJ}$ND4:^$KMQ$$$k(B |
$B!!(B |
3021 | $B%D%`%i$N@8Lt(B $B=$<#%V%7Kv(B($BD4:^MQ(B) |
$B-!!V8zG=!&8z2L!W(B $B4AJ}=hJ}$ND4:^$KMQ$$$k(B |
$B!!(B |
501 | $B%D%`%i;g1@9Q(B $B$7$&$s$3$&(B |
$B-!!V8zG=!&8z2L!W(B $B2P=}!"<&3K$K$h$kaVDK!"fjLgNu=}(B $B-"!V;HMQL\I8!a>Z!W(B $BHf3SE*BNNO$NDc2<$7$??M$G!"J,HgJ*$N>/$J$$>l9g$KMQ$$$k!#(B $B#1!K2P=}!"<&3K$K$h$kaVDK!"fjLgNv=}$KMQ$$$k!#(B $B-#!VLt8z!&LtM}!W(B $BAO=}<#L~B%?J:nMQ!J%i%C%H!"%^%&%9!K(B |
$BF|6I%4%^L}!D(B100.0g,$BF|6I%7%3%s!D(B10.0g,$BF|6I%H%&%-!D(B10.0g$B!!F|6I%5%i%7%_%D%m%&!D(B27.0g,$BF|6IFZL}!D(B1.8g |
$B$*Ld$$9g$o$;$O!"(B
$B4AJ}$r8=BeIB$K3h$+$9!*4AJ}@lLg!!Bg;34AJ}F2Lt6I(B
0283-22-1574$B!JBg;34AJ}$G!"%$%4!&IT0B!&%J%7!K(B
$B$^$G!"$*5$7Z$K$*Ld$$9g$o$;$/$@$5$$!#(B
$BBg;34AJ}F2Lt6I(B
$B4AJ}7r9/AjCL%3!<%J!<$X!"%/%j%C%/!*(B
$B:4LnLq=|$1Bg;UDL$j$N4AJ}@lLg!"Bg;34AJ}F2Lt6I!!(BWeb-Page
$B$X!"#G#o!*!*!*(B
$B0eLtIJ$O;HMQ>e$NCm0U$r$*FI$_$$$?$@$-!"@5$7$/$*;H$$$/$@$5$$!#(B
$B$*Gc$$5a$a$N:]$K$O!"4AJ}$r8=BeIB$K3h$+$9(B $B4AJ}@lLg(B $BBg;34AJ}Lt6I$K!"$*5$7Z$K$4AjCL$/$@$5$$!#(B
$B!V%$%s%?!<%M%C%H$G8+$?!*!W(B
$B$H$*OC$/$@$5$$!#(B
$B!JCm0U!K(B
$B4AJ}@lLg!!Bg;34AJ}F2Lt6I$N!!87A*!"4AJ}Lt!"7r9/?)IJ$N$4CmJ8$O!"Bg;34AJ}Lt6I$K!"D>@\!"$*EEOC!"(BFAX$B!"(BE-mail
$B$K$F$4MQL?$/$@$5$$!#(B
$B$*EEOC!'(B0283-22-1574$B!"(BFAX$B!'(B0283-22-1607$B!"(BE-mail:ohyama@poem.ocn.ne.jp
$B$*BT$ACW$7$F$*$j$^$9!#(B
$B!VBg;34AJ}F2(B $B4AJ}0e3X$H4AJ}7r9/AjCL!W(B
$B!!!!!!!!!!(B$B!!Bg;34AJ}F2Lt6I$NF@0U$H$9$kIB5$!"Bg;34AJ}F2Lt6I$K4AJ}AjCL$N$"$k$4IB5$0lMw!"(B
$B!!!!Bg;34AJ}F2Lt6I(B $B4AJ}7r9/AjCLAk8}!"0e3XGn;NBg;3Gn9T@h@8!"0e3XGn;N>.>>Lw90@h@8$N$4>R2p(B
" THE KAMPO " $B4AJ}(B
$B!!4AJ}Lt(B, How the Japanese Updated Traditional
Herbal Medicine
$B!c4AJ}Lt$N$4I~MQ$r$*9M$($N3'MM$X$N$*4j$$!*!d(B
$B!v4AJ}Lt$N$4I~MQ$K4X$7$^$7$F$O!"(B
$B!V;HMQ>e$NCm0U!W$r$h$/FI$_!"!VMQK!!&MQNL!W$r$h$/
$B$^$?!":#2s!";O$a$F!"4AJ}Lt$N$4I~MQ$r4uK>$5$l$k$*5RMM$O!"(B
$B2<5-!"Ld?GI=$KI,MW;v9`$r5-F~$7$FAw?.$9$k$+!"(B
$B4AJ}AjCL$*?=$79~$_%U%)!<%`(B
$B$*EEOC$K$F!"D>@\!"Bg;34AJ}Lt6I$K!"$4AjCL$/$@$5$$!#(B
$B>I>u!&BN\$7$/$*;G$$$7$?>e$G!"E,@Z$J4AJ}Lt$r%"%I%P%$%9$5$;$FD:$-$^$9!#(B
$B!JBg;34AJ}Lt6I(B / $BL5NA4AJ}AjCLEEOC(B $B#0#2#8#3(B-$B#2#2(B-$B#1#5#7#4(B
/ $B#9!'#0#0!A#1#9!'#0#0!K(B
$B!cCm0U!d(B
$BBg;34AJ}Lt6I!"%G%8%?%kE9J^$G!"$*
$B0J>e!"$h$m$7$/$*4j$$CW$7$^$9!#(B
E-mail to Dr. Ohyama Kampo Pharmacy.
$B!!4AJ}$r8=BeIB$K3h$+$9!*!!4AJ}@lLg!!Bg;34AJ}Lt6I%G%8%?%kE9J^$X!*(B
$BBg;34AJ}F2Lt6I(B $B")(B327-0026$B!!FJLZ8):4Ln;T6b20CgD9D.#2#4#3#2(B
TEL$B!u(BFAX : 0283-22-1574$B!!(B E-mail : ohyama@poem.ocn.ne.jp
$B!!(B$B!!(B